The Vitreous and Vitreoretinal Interface

Author: Charles L. Schepens,Adolph Neetens

Publisher: Springer Science & Business Media

ISBN: 1475719019

Category: Medical

Page: 315

View: 7608

Ophthalmic researchers and clinicians alike increasingly are recognizing the importance of the vitreous body in the physiology, biochemistry, and pathology of the inner eye. The Vitreous and Vitreoretinal Interface, with contributions by vitreoretinal surgeons and laboratory eye researchers, presents the most up-to-date clinically relevant data. This book provides evidence of the vitreous body's significant role in preserving retinal homeostasis, as well as the close connection between vitreous traction and such conditions as retinal inflammation, retinal vascular occlusions, macular edema, proliferative diabetic retinopathy, and giant retinal tears. The particular vitreal changes that occur in aphakia, myopia, retinitis pigmentosa, and idiopathic giant retinal breaks, as well as recent advances in open-sky vitreous surgery and in the search for useful vitreous substitutes are discussed.

Medical Retina

Update 2017

Author: F. Bandello,G. Querques,A. Loewenstein

Publisher: Karger Medical and Scientific Publishers

ISBN: 3318060682

Category: Medical

Page: 86

View: 5216

In the 'ESASO Course Series' the essentials of the courses of the European School for Advanced Studies in Ophthalmology (ESASO) are made available to interested ophthalmologists, optometrists, technicians, and residents all over the world. In the seven years since the first edition of this book was published, major advances in diagnostics and management strategies of retinal diseases have evolved. This updated and revised edition takes this into account and focuses on the significant developments of preferred practice for diabetic retinopathy and dry and neovascular AMD. It further discusses pathology, imaging, and visualization of retinal diseases. In addition it considers biologic disease markers and new drugs being developed. Medical retina specialists who wish to stay abreast of the constantly changing world of medical retina will find this publication a must-read.

The Vitreous

Structure, Function, and Pathobiology

Author: J. Sebag

Publisher: Springer Science & Business Media

ISBN: 1461389089

Category: Medical

Page: 173

View: 2951

The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how the vitreous is composed and what role it plays in normal physiology. Over the years, however, many studies have produced independent findings concerning vitreous biochemistry, structure, and physiology. The Vitreous organizes these findings into a well-constructed compendium that not only addresses the most current scientific knowledge, but also reviews historical perspec tives in a manner that lends richness to the scope of the book. The first few chapters present an exhaustive, yet readable, review of the body of scientific data that have come from laboratories and researchers throughout the world. Extensive bibliographies direct interested readers further into specific aspects of the basic science of the vitreous. Chapter II: "Embryology" and Chapter IV: "Structure" present a novel organizational approach to assembling and presenting data in an integrated manner. Chapter V: "Functions" and Chapter VI: "Development and Aging" introduce fresh perspectives on the importance of the vitreous as some thing more than a vestigial space filler within the eye.

Pharmacology and Vitreoretinal Surgery

Author: Arnd Gandorfer

Publisher: Karger Medical and Scientific Publishers

ISBN: 3805590296

Category: Medical

Page: 101

View: 3072

Since the advent of pars plana vitrectomy, immense technical advances in the treatment of retinal diseases have been made. However, some mechanically based limitations of vitreoretinal surgery may result in incomplete removal of the vitreous, especially at the vitreoretinal interface and at the vitreous base. Here, pharmacology can be of assistance. For instance, enzymes that cleave the vitreoretinal junction without damaging the retina or which induce liquefaction may be applied. Neuroprotective and antiproliferative agents may hold the promise of preserving neuronal function when the retina is detached or when proliferative vitreoretinopathy or proliferative diabetic retinopathy has developed. Earlier intervention is possible and can save visual function before the retinal cytoarchitecture is destroyed. Consequently, pharmacologic vitreolysis will change the current concepts of treating retinal and macular diseases.This volume is the first comprehensive up-date on pharmacology-assisted vitreoretinal surgery. Researchers in the fields of medical and surgical retina as well as retinal specialists and vitreoretinal surgeons in clinics will benefit from this topical summary.

Ryan's Retina E-Book

Author: Andrew P. Schachat,Charles P. Wilkinson,David R. Hinton,SriniVas R. Sadda,Peter Wiedemann

Publisher: Elsevier Health Sciences

ISBN: 0323401988

Category: Medical

Page: 2384

View: 1488

The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.

Vitreous

in Health and Disease

Author: J. Sebag

Publisher: Springer

ISBN: 1493910868

Category: Medical

Page: 925

View: 5100

The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag's first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspectives in a manner that lends richness to the scope of the book. Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; Physiology and Phamacotherapy; Posterior Vitreo-Retinal Surgery; Peripheral Vitreo-Retinal Surgery; and Pharmacologic Vitreolysis. With a foreword by Coleman & Lincoff and an introduction by Wallace Foulds, Sebag's latest tome on vitreous is destined to be the authoritative text for years to come.

Medical Retina

Focus on Retinal Imaging

Author: Frank G Holz,Richard F. Spaide

Publisher: Springer Science & Business Media

ISBN: 9783540855408

Category: Medical

Page: 227

View: 8188

Recent advances in ophthalmic imaging technology have revolutionized fundus examination and contributed significantly in elucidating the pathophysiology of retinal diseases and improving their diagnosis and treatment. It is therefore fitting that this detailed full-color textbook in the Medical Retina series is devoted to ocular imaging. The volume reviews in detail the role of both established and novel forms of imaging, and is designed to be of benefit to clinicians and researchers alike. All of the chapters have been written by internationally recognized experts at the forefront of their fields. The result is a comprehensive, state-of-the-art overview of retinal imaging that should prove informative and useful for everyone interested in the retina. Topics include: •Spectral domain optical coherence tomography (SD-OCT) of macular diseases •Comparison of OCT equipment •Simultaneous SD-OCT and confocal SLO imaging •Ultra-widefield imaging °Autofluorescence imaging •Near-infrared imaging •Macular pigment imaging •Metabolic mapping •Imaging of the choroid •Imaging the vitreous and the vitreoretinal interface with SD-OCT •New developments in OCT technology •Molecular imaging

Retinal Pharmacotherapeutics

Retinal Pharmacotherapeutics

Author: Q.D. Nguyen,E.B. Rodrigues,M.E. Farah,W.F. Mieler,D.V. Do

Publisher: Karger Medical and Scientific Publishers

ISBN: 3318055654

Category: Medical

Page: 408

View: 7329

The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading.

Annual Update in Intensive Care and Emergency Medicine 2018

Author: Jean-Louis Vincent

Publisher: Springer

ISBN: 3319736701

Category: Medical

Page: 709

View: 6197

The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Gass' Atlas of Macular Diseases E-Book

Author: Anita Agarwal

Publisher: Elsevier Health Sciences

ISBN: 1455733458

Category: Medical

Page: 1378

View: 6885

The Fifth Edition of Gass' Atlas of Macular Diseases, by Dr. Anita Agarwal, provides expert diagnostic guidance on macular disorders and quickly brings you up to date on this evolving specialty. Using a case-based approach, it richly depicts a full range of retina and macular diseases, including new infectious, degenerative, and dystrophic conditions. Take advantage of the latest imaging technologies to identify common and rare disorders, and confirm difficult diagnoses with the aid of more than 5,500 high-quality images. Rely on the same unique, richly illustrated case-descriptive format–encompassing history, clinical examination, and follow-up–that popularized the original book by the late Dr. Donald Gass, the famed ophthalmologist whose clinical expertise set new standards in macular diagnosis. Get expert diagnostic guidance under the new authorship of Dr. Anita Agarwal, a protégé of Dr. Gass who has compiled the ultimate collection of images and hard-to-find case studies from around the world. Visualize the conditions you’re likely to see in practice and confirm your diagnoses by comparing your clinical findings to more than 5,500 images and illustrations (over 3,500 in full color). Obtain thorough advice on imaging and recognition of a full range of common and rare macular diseases using the latest approaches including fluorescein angiography, optical coherence tomography (OCT), indocyanine green (ICG), and fundus autofluorescence.

Vitreous

in Health and Disease

Author: J. Sebag

Publisher: Springer

ISBN: 1493910868

Category: Medical

Page: 925

View: 7121

The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag's first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspectives in a manner that lends richness to the scope of the book. Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; Physiology and Phamacotherapy; Posterior Vitreo-Retinal Surgery; Peripheral Vitreo-Retinal Surgery; and Pharmacologic Vitreolysis. With a foreword by Coleman & Lincoff and an introduction by Wallace Foulds, Sebag's latest tome on vitreous is destined to be the authoritative text for years to come.

Handbook of Pediatric Retinal Disease

Author: Kenneth W. Wright,Peter H. Spiegel,Lisa Thompson

Publisher: Springer Science & Business Media

ISBN: 0387279334

Category: Medical

Page: 494

View: 6411

Based on Dr. Wright’s classic major reference, Handbook of Pediatric Retinal Disease outlines the latest findings in diagnosing retinal disorders in children's and the best available treatment options. Distilling the essentials of these somewhat uncommon discorders and diseases into a portable, complete and authorative pocket reference, this handbook offers a complete picture of how to best treat pediatric patients. Specifically, the introductory chapters on the specifics of pediatric ophthalmology (embryology, post-natal development and the pediatric exam) will help newcomers to pediatric practice fully grasp the subtle differences in pediatric care. The chapters are written by leading experts in the field and are presented in a user-friendly format, relying on heavily illustrated in color plates, clincally helpful tables, charts, and decision-making guidelines. This approach will enable the practitioner (whether specialist or generalist) to make the most accurate diagnosis and choose the most effective treatment option.

Manual of Retinal Diseases

A Guide to Diagnosis and Management

Author: Carlos A. Medina,Justin H. Townsend,Arun D. Singh

Publisher: Springer

ISBN: 3319204602

Category: Medical

Page: 632

View: 8830

This book is a comprehensive source of authoritative information on the clinical features,diagnosis, differential diagnosis, and management of medical and surgical retinal diseases. The Manual has 122 chapters, organized in 18 sections covering medical and surgical aspects of retinal diseases such as trauma, AMD, Uveitis, infections, endophthalmitis, pediatric diseases, dystrophies, and tumors. Easy-to-read chapters convey the fundamental concepts with the aid of clinical photographs, imaging studies (including fluorescein and indocyanine angiograms, ultrasonograms, CT scans, and MRI scans) and tables. The manual is of value to a wide range of practitioners and trainees, including students,residents, fellows and ophthalmologists who treat retinal diseases.

Retina E-Book

Author: Stephen J. Ryan,Andrew P. Schachat,Charles P. Wilkinson,David R. Hinton,SriniVas R. Sadda,Peter Wiedemann

Publisher: Elsevier Health Sciences

ISBN: 1455737801

Category: Medical

Page: 2564

View: 7744

Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.

The Retinal Müller Cell

Structure and Function

Author: Vijay Sarthy,Harris Ripps

Publisher: Springer Science & Business Media

ISBN: 0306468417

Category: Medical

Page: 278

View: 9837

The human brain contains more than a billion neurons which interconnect to form networks that process, store, and recall sensory information. These neuronal activities are supported by a group of accessory brain cells coll- tively known as neuroglia. Surprisingly, glial cells are ten times more - merous than neurons, and occupy more than half the brain volume (Hydén, 1961). Although long considered a passive, albeit necessary, component of the nervous system, many interesting and unusual functional properties of glial cells are only now being brought to light. As a result, the status of these cellular elements is approaching parity with nerve cells as a subject for experimental study. The term glia (or glue) seems today to be a misnomer in view of the diverse functions attributed to glial cells. Experimental studies in the last three decades have clearly established that the behavior of glial cells is far from passive, and that they are at least as complex as neurons with regard to their membrane properties. In addition, glial cells are of importance in signal processing, cellular metabolism, nervous system development, and the pathophysiology of neurological diseases. The Müller cell of the ver- brate retina provides a splendid example of an accessory cell that exhibits features illustrating every aspect of the complex behavior now associated with glial cells.

Diabetic Retinopathy

Current Pharmacologic Treatment and Emerging Strategies

Author: Michael W. Stewart

Publisher: Springer

ISBN: 9811035091

Category: Medical

Page: 268

View: 8290

A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option. Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed.

Retinal Pharmacotherapy E-Book

Author: Quan Dong Nguyen,Eduardo Buchele Rodrigues,Michel Eid Farah,William F. Mieler

Publisher: Elsevier Health Sciences

ISBN: 0702047406

Category: Medical

Page: 408

View: 5261

Retinal Pharmacotherapy is the first comprehensive book devoted to pharmacologic agents and their rationale and mechanisms of action in selected retinal and uveitic diseases. Drs. Quan Dong Nguyen, Eduardo Buchele Rodrigues, Michel Eid Farah, and William F. Mieler lead an international team of expert contributors to present up-to-date knowledge of new drugs on the market, the science behind the drugs, evidence of how the drugs work, and the reasons why they are effective or not. This user-friendly, all-in-one reference provides you with easy access to practical information on the effective and appropriate use of pharmacologic agents in the management of retinal diseases. Covers all new and existing retinal drugs to keep you current in this expanding area of the treatment of retinal diseases. Discusses the background behind retinal drugs and the various pathways of how they work so you can make thoroughly informed clinical decisions. Presents 400 color photographs and line drawings that illustrate disease appearance before and after treatment and clarify difficult key concepts. Features contributors from Europe, North America, South America, the Middle East, Asia, and Australia for an international approach. Identifies and emphasizes key points clearly in each chapter to improve comprehension and make finding information easier.

New Trends in Ophthalmology: Medical and Surgical Management

Author: Samuel Boyd,Benjamin F Boyd

Publisher: JP Medical Ltd

ISBN: 9962678625

Category: Medical

Page: 334

View: 9130

New Trends in Ophthalmology presents ophthalmologists with the most recent technological developments in this rapidly advancing field. Each chapter explains current diagnosis and medical and surgical management of different ocular disorders and diseases, including cataract surgery, glaucoma treatment and lens implant surgery. Presented in an easy to follow format, this comprehensive manual is enhanced by nearly 400 clinical photographs, diagrams and tables. Key points Comprehensive guide to latest technological developments in ophthalmology Presents medical and surgical management of numerous ocular diseases and disorders Internationally recognised author and editor team, predominantly from Europe and the USA Includes nearly 400 full colour clinical photographs, diagrams and tables

Diseases of the Vitreo-Macular Interface

Author: Aniz Girach,Marc D. de Smet

Publisher: Springer Science & Business Media

ISBN: 3642400345

Category: Medical

Page: 122

View: 8189

This clinically oriented book is the first to be devoted wholly to the diagnosis and treatment of vitreo-macular interface disease, characterized by a combination of vitreo-macular adhesion (VMA) and vitreo-macular traction (VMT) that is implicated in a variety of disorders. World-renowned experts in the field discuss epidemiologic, anatomic, and physiologic aspects, document the findings obtained with newer imaging techniques, such as spectral domain optical coherence tomography, describe the treatment options, and report on the results of preclinical and clinical trials, including some previously unpublished findings. This book will prove invaluable for ophthalmologists as we advance toward a future in which treatments of diseases such as age-related macular degeneration and diabetic retinopathy will likely require adjunctive therapy to tackle VMA/VMT concurrently.