The Making of a Fly

The Genetics of Animal Design

Author: P. A. Lawrence

Publisher: Wiley-Blackwell

ISBN: 9780632030484

Category: Science

Page: 240

View: 583

Understanding how a multicellular animal develops from a single cell (the fertilized egg) poses one of the greatest challenges in biology today. Development from egg to adult involves the sequential expression of virtually the whole of an organism's genetic instructions both in the mother as she lays down developmental cues in the egg, and in the embryo itself. Most of our present information on the role of genes in development comes from the invertebrate fruit fly, Drosophila. The two authors of this text (amongst the foremost authorities in the world) follow the developmental process from fertilization through the primitive structural development of the body plan of the fly after cleavage into the differentiation of the variety of tissues, organs and body parts that together define the fly. The developmental processes are fully explained throughout the text in the modern language of molecular biology and genetics. This text represents the vital synthesis of the subject that many have been waiting for and it will enable many specific courses in developmental biology and molecular genetics to focus on it. It will appeali to 2nd and 3rd year students in these disciplines as well as in biochemistry, neurobiology and zoology. It will also have widespread appeal among researchers. Authored by one of the foremost authorities in the world. A unique synthesis of the developmental cycle of Drosophila - our major source of information on the role of genes in development. Designed to provide the basis of new courses in developmental biology and molecular genetics at senior undergraduate level. A lucid explanation in the modern language of the science.

Lords of the Fly

Drosophila Genetics and the Experimental Life

Author: Robert E. Kohler

Publisher: University of Chicago Press

ISBN: 9780226450636

Category: Science

Page: 321

View: 7759

"One of the most productive of all laboratory animals, Drosophila has been a key tool in genetics research for nearly a century. At the center of Drosophila culture from 1910 to 1940 was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges, who, by inbreeding fruit flies, created a model laboratory creature - the 'standard' fly. By examining the material culture and working customs of Morgan's research group, [the author] brings to light essential features of the practice of experimental science. [This book] takes a broad view of experimental work, ranging from how the fly was introducted into the laboratory and how it was physically redesigned for use in genetic mapping, to how the 'Drosophilists' organized an international network for exchanging fly stocks that spread their practices around the world"--Back cover.

Fly

The Unsung Hero of Twentieth-Century Science

Author: Martin Brookes

Publisher: Harper Collins

ISBN: 0060936797

Category: Science

Page: 224

View: 7040

A short biography of a creature that changed science. There's a buzz in the air, the sound of a billion wings vibrating to the tune of scientific success. For generations, the fruit fly has been defining biology's major landmarks. From genetics to development, behavior to aging, and evolution to the origin of the species, it has been a key and, outside academic circles, an unaccredited player in some of the twentieth century's greatest biological discoveries. In fact, everything from gene therapy to cloning and the Human Genome Project is built on the foundation of fruit fly research. This witty, irreverent biography of the fruit fly provides a broad introduction to biology as well as a glimpse into how one short life has informed scientific views on such things as fundamentals of heredity, battle of the sexes, and memory.

Time, Love , Memory

A Great Biologist and His Quest for the Origins of Behavior

Author: Jonathan Weiner

Publisher: Vintage

ISBN: 0804153361

Category: Biography & Autobiography

Page: 320

View: 4817

How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives. Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

Molecular Biology of the Cell

Author: Bruce Alberts

Publisher: Garland Science

ISBN: 1317563743

Category: Science

Page: 1464

View: 7012

As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Designer Genes

A New Era in the Evolution of Man

Author: Steven Potter

Publisher: Random House Incorporated

ISBN: 140006905X

Category: Medical

Page: 188

View: 2205

An expert in human gene modification and research explores the ethical questions surrounding science's new power to guide the genetic destiny of humanity.

Engineering Animals

Author: Mark Denny,Alan McFadzean

Publisher: Harvard University Press

ISBN: 0674060857

Category: Science

Page: 386

View: 6095

From an engineer’s perspective, how do specialized adaptations among living things really work? Writing with wit and a richly informed sense of wonder, Denny and Alan offer an expert look at animals—including humans—as works of evolutionary engineering, each exquisitely adapted to a specific manner of survival.

From DNA to Diversity

Molecular Genetics and the Evolution of Animal Design

Author: Sean B. Carroll,Jennifer K. Grenier,Scott D. Weatherbee

Publisher: John Wiley & Sons

ISBN: 1118685202

Category: Science

Page: 272

View: 9114

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa. Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels. Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species. Provides in-depth focus on key concepts through well-developed case studies. Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary. Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology. An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at [email protected] for more information.

The Selfish Gene

Author: Richard Dawkins

Publisher: Oxford University Press, USA

ISBN: 9780192860927

Category: Literary Criticism

Page: 352

View: 5122

An ethologist shows man to be a gene machine whose world is one of savage competition and deceit

The Incredible Unlikeliness of Being: Evolution and the Making of Us

Author: Alice Roberts

Publisher: Heron Books

ISBN: 162365808X

Category: Science

Page: 432

View: 5306

In this compulsively readable book, Dr. Alice Roberts lays out the miraculously strange way in which the human body grows from a chemical (DNA) into a living, sentient being. A longtime professor and well-known TV presenter, Dr. Roberts is also an author of unusual ability, capable of synthesizing complex ideas and packing dense scientific information into lucid, beautiful prose. Bringing together the latest scientific discoveries and drawing on interviews with scientists from around the world, Dr. Roberts illustrates that our evolution has resulted in something that is awe-inspiring yet far from perfect. Our embryonic development is a quirky mix of new and old, with strokes of genius alongside accommodated glitches and imperfections that are all inherited from distant ancestors. For instance, our development and evolutionary past explains why, as embryos, we have what look like gills, and as adults we suffer from back pain. This is a tale of discovery, about ourselves and our environment, that explores why and how we have developed as we have, looking at the development of human physiognomy through the various lenses of embryology, genetics, anatomy, evolution, and zoology. It combines the remarkable set of skills Alice Roberts possesses as a medical doctor, anatomist, osteoarchaeologist, and writer. As Richard Dawkins put it, the reader emerges from her book "entertained and with a deeper understanding of yourself."

The Gene

An Intimate History

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

ISBN: 1476733538

Category: Medical

Page: 608

View: 5212

THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

Why Is a Fly Not a Horse?

Author: Giuseppe Sermonti

Publisher: Discovery Inst

ISBN: 9780963865489

Category: Science

Page: 176

View: 5590

This book's Italian title, Dimenticare Darwin, means "Forget Darwin," and its prologue bears the title "Evolution is dead!" The author, Dr. Giuseppe Sermonti, is a respected Italian biologist who boldly shatters the myth that all critics of Darwinian evolution are American religious fundamentalists. This delightful little book is loaded with scientific facts that aren't taught in standard biology classes, but it is also full of history and poetry. Why is a Fly Not a Horse? does not have all the answers, but it asks many of the right questions-in a style that is both entertaining and inspiring. Giuseppe Sermonti is retired Professor of Genetics at the University of Perugia. He discovered genetic recombination in antibiotic-producing Penicillium and Streptomyces and was Vice President at the XIV International Congress of Genetics (Moscow, 1980). Sermonti is Chief Editor of Rivista di Biologia/Biology Forum, one of the oldest still-published biology journals in the world, and he has published seven other books, including Dopo Darwin (After Darwin), with R. Fondi (1980-1984).

Encyclopedia of Insects

Author: Vincent H. Resh,Ring T. Cardé

Publisher: Academic Press

ISBN: 9780080920900

Category: Science

Page: 1168

View: 2570

Awarded Best Reference by the New York Public Library (2004), Outstanding Academic Title by CHOICE (2003), and AAP/PSP 2003 Best Single Volume Reference/Sciences by Association of American Publishers' Professional Scholarly Publishing Division, the first edition of Encyclopedia of Insects was acclaimed as the most comprehensive work devoted to insects. Covering all aspects of insect anatomy, physiology, evolution, behavior, reproduction, ecology, and disease, as well as issues of exploitation, conservation, and management, this book sets the standard in entomology. The second edition of this reference will continue the tradition by providing the most comprehensive, useful, and up-to-date resource for professionals. Expanded sections in forensic entomology, biotechnology and Drosphila, reflect the full update of over 300 topics. Articles contributed by over 260 high profile and internationally recognized entomologists provide definitive facts regarding all insects from ants, beetles, and butterflies to yellow jackets, zoraptera, and zygentoma. * 66% NEW and revised content by over 200 international experts * New chapters on Bedbugs, Ekbom Syndrome, Human History, Genomics, Vinegaroons * Expanded sections on insect-human interactions, genomics, biotechnology, and ecology * Each of the 273 articles updated to reflect the advances which have taken place in entomology research since the previous edition * Features 1,000 full-color photographs, figures and tables * A full glossary, 1,700 cross-references, 3,000 bibliographic entries, and online access save research time * Updated with online access

GMO Sapiens

The Life-Changing Science of Designer Babies

Author: Paul Knoepfler

Publisher: World Scientific

ISBN: 981466703X

Category: Science

Page: 250

View: 6483

' Genetically modified organisms (GMOs) including plants and the foods made from them, are a hot topic of debate today, but soon related technology could go much further and literally change what it means to be human. Scientists are on the verge of being able to create people who are GMOs. Should they do it? Could we become a healthier and ''better'' species or might eugenics go viral leading to a real, new world of genetic dystopia? GMO Sapiens tackles such questions by taking a fresh look at the cutting-edge biotech discoveries that have made genetically modified people possible. Bioengineering, genomics, synthetic biology, and stem cells are changing sci-fi into reality before our eyes. This book will capture your imagination with its clear, approachable writing style. It will draw you into the fascinating discussion of the life-changing science of human genetic modification. Contents:An Introduction to Playing GodThe Birth and Explosive Growth of GMOsHuman CloningBuild-a-Baby Better via GeneticsDIY Guide to Creating GMO SapiensEugenics and TranshumanismCultural Views on Human Genetic ModificationGMO Sapiens Today and Tomorrow Readership: Undergraduate biology majors, graduate biology majors, non-experts interested in GMOs, biologists and teenagers interested in cloning and human genetic modification. Key Features:Books on this hot new topic of creating GMO people are rare, tend to be out-of-date, or have narrow topic rangesThe goal of this book is to educate and entertain an educated lay audience about human genetic modificationKeywords:GMO;Genetically Modified Organism;GMO Sapien;Cloning;Genomics;Designer Babies;Mitochondrial Transfer;Stem Cells;Infertility "What I find troubling, exciting but scary, is that I find myself agreeing with an undertone, I do not support human germline genetic modification but with all the new information and perspectives available to me I have found myself questioning my own views and will be watching any developments with a fascinated interest I would rather not admit to." The NODE '

Genetics and Evolution of Infectious Diseases

Author: Michel Tibayrenc

Publisher: Elsevier

ISBN: 0128001534

Category: Medical

Page: 686

View: 4431

Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

How Genes Influence Behavior

Author: Jonathan Flint,Ralph J. Greenspan,Kenneth S. Kendler

Publisher: OUP Oxford

ISBN: 9780199559909

Category: Psychology

Page: 264

View: 7095

This book is a unique introduction to behavioral genetics, which offers unparalleled insights into how the topic is probed using evidence from humans and the major model organisms. It also demonstrates the major impact that neurobiology is having on our understanding of the field, to give a true depiction of behavioral genetics in the 21st century.