Genetics

Analysis of Genes and Genomes

Author: Daniel L. Hartl,Elizabeth W. Jones

Publisher: Jones & Bartlett Learning

ISBN: 9780763758684

Category: Science

Page: 763

View: 2553

This handbook covers all dimensions of breast cancer prevention, diagnosis, and treatment for the non-oncologist. A special emphasis is placed on the long term survivor.

Student Solutions Manual and Supplemental Problems to Accompany Genetics: Analysis of Genes and Genomes

Author: Daniel L. Hartl,Maryellen Ruvolo

Publisher: Jones & Bartlett Publishers

ISBN: 1449644708

Category: Science

Page: 392

View: 9557

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Genetics

Author: Daniel L. Hartl,Maryellen Ruvolo

Publisher: Jones & Bartlett Publishers

ISBN: 1449626106

Category: Science

Page: 800

View: 3506

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Genetics, Analysis of Genes and Genomes

Author: CTI Reviews

Publisher: Cram101 Textbook Reviews

ISBN: 1478429089

Category: Education

Page: 166

View: 4969

Facts101 is your complete guide to Genetics, Analysis of Genes and Genomes. In this book, you will learn topics such as as those in your book plus much more. With key features such as key terms, people and places, Facts101 gives you all the information you need to prepare for your next exam. Our practice tests are specific to the textbook and we have designed tools to make the most of your limited study time.

Analysis of Genes and Genomes

Author: Richard J. Reece

Publisher: Halsted Press

ISBN: 9780470843796

Category: Science

Page: 469

View: 4073

Analysis of GenesA and Genomes is a clear introduction to the theoretical and practical basis of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented. Newer technologies such as DNA macro and macroarrays, proteomics and bioinformatics are introduced in later chapters helping students to analyse and understand the vast amounts of data that are now available through genome sequence and function projects. Aimed at students with a basic knowledge of the molecular side of biology, this will be invaluable to those looking to better understand the complexities and capabilities of these important new technologies. A modern post-genome era introduction to key techniques used in genetic engineering. An example driven past-to-present approach to allow the experiments of today to be placed in an historical context Beautifully illustrated in full colour throughout. Associated website including updates, additional content and illustrations

Genetic Analysis of Complex Disease

Author: Jonathan L. Haines,Margaret A. Pericak-Vance

Publisher: John Wiley & Sons

ISBN: 0471781134

Category: Science

Page: 512

View: 5548

Second Edition features the latest tools for uncovering thegenetic basis of human disease The Second Edition of this landmark publication bringstogether a team of leading experts in the field to thoroughlyupdate the publication. Readers will discover the tremendousadvances made in human genetics in the seven years that haveelapsed since the First Edition. Once again, the editorshave assembled a comprehensive introduction to the strategies,designs, and methods of analysis for the discovery of genes incommon and genetically complex traits. The growing social, legal,and ethical issues surrounding the field are thoroughly examined aswell. Rather than focusing on technical details or particularmethodologies, the editors take a broader approach that emphasizesconcepts and experimental design. Readers familiar with theFirst Edition will find new and cutting-edge materialincorporated into the text: Updated presentations of bioinformatics, multiple comparisons,sample size requirements, parametric linkage analysis, case-controland family-based approaches, and genomic screening New methods for analysis of gene-gene and gene-environmentinteractions A completely rewritten and updated chapter on determininggenetic components of disease New chapters covering molecular genomic approaches such asmicroarray and SAGE analyses using single nucleotide polymorphism(SNP) and cDNA expression data, as well as quantitative trait loci(QTL) mapping The editors, two of the world's leading genetic epidemiologists,have ensured that each chapter adheres to a consistent and highstandard. Each one includes all-new discussion questions andpractical examples. Chapter summaries highlight key points, and alist of references for each chapter opens the door to furtherinvestigation of specific topics. Molecular biologists, human geneticists, geneticepidemiologists, and clinical and pharmaceutical researchers willfind the Second Edition a helpful guide to understanding thegenetic basis of human disease, with its new tools for detectingrisk factors and discovering treatment strategies.

Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Author: Philip Meneely

Publisher: Oxford University Press, USA

ISBN: 0199651817

Category: Medical

Page: 580

View: 9771

How do we know what role a particular gene has? How do some genes control the expression of others? How do genes interact to form gene networks? With its unique integration of genetics and molecular biology, Genetic Analysis probes fascinating questions such as these, detailing how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles, model organisms, and epigenetics, the book goes on to explorethe use of gene mutations and the analysis of gene expression and activity. A discussion of the genetic structure of natural populations follows, before the interaction of genes during suppression and epistasis, how we study gene networks, and personalized genomics are considered. Drawing on the latest experimental tools, including microarrays, RNAi screens, and bioinformatics approaches, Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight. We are in an age where, despite knowing so much about biological systems, we are just beginning to realise how much more there is still to understand. Genetic Analysis is the ideal guide to how we can use the awesome power of molecular genetics to further our understanding. Online Resource Centre: The Online Resource Centre to accompany Genetic Analysis features the following resources for teachers and students: For students: * Topical updates - key updates on topics or tools presented in the book, to keep you up-to-date with the latest developments in the field. * Additional case studies and text boxes to complement and add to those found in the book. * Practice problems, to test the reader's knowledge of the concepts presented, and help to master them. For registered adopters ofthe book: * Figures from the book in electronic format, ready to download. * Journal clubs - suggested papers and discussion questions linked to topics covered in the book.

Genetics and Genomics of Soybean

Author: Gary Stacey

Publisher: Springer Science & Business Media

ISBN: 9780387722993

Category: Science

Page: 407

View: 410

Soybean genomics is of great interest as one of the most economically important crops and a major food source. This book covers recent advances in soybean genome research, including classical, RFLP, SSR, and SNP markers; genomic and cDNA libraries; functional genomics platforms; genetic and physical maps; and gene expression profiles. The book is for researchers and students in plant genetics and genomics, plant biology and pathology, agronomy, and food sciences.

The Zebrafish: Genetics and Genomics

The Zebrafish, Volume II Genetics and Genomics

Author: N.A

Publisher: Academic Press

ISBN: 9780080859583

Category: Science

Page: 396

View: 4872

This is the second volume of a two-volume, comprehensive treatment of the methodologies used in researching the zebrafish, an emerging vertebrate model system. The text includes discussions on development, genetic methodologies, and model applications. Key Features * Details state-of-the-art zebrafish protocols in a single-source reference * Presents methods and reagents in user-friendly format * Delineates critical steps and pitfalls of he procedures * Illustrates techniques with full-color plates * Summarizes many new and interesting developmental mutants * Includes appendices with strain information and a compendium of zebrafish World Wide Web sites * Relevant to clinicians interested in vertebrate models of human congenital diseases

Cardiovascular Genetics and Genomics in Clinical Practice

Author: Donna K. Arnett, PhD,Sanjiv J. Shah, MD

Publisher: Demos Medical Publishing

ISBN: 1617051780

Category: Medical

Page: 246

View: 3454

Weighted Numerical Score: 100 - 5 Stars! This is a systematic guide to cardiovascular genetics and genomics from basic concepts to clinical application. It organizes a large volume of information from an active area of research, which holds promise for future discovery. --Doody's Reviews Cardiovascular Genetics and Genomics in Clinical Practice presents clinical cases to illuminate basic concepts of cardiovascular genetics and genomics as practitioners encounter them in day-to-day practice. The unique use of real-world case discussions facilitates the memorization and understanding of basic principles, which can be more readily applied to actual cases. Cardiovascular Genetics and Genomics in Clinical Practice features a step-by-step learning process that begins with an easy-to-understand "primer" of basic scientific concepts regarding cardiovascular genetics and genomics followed by state-of-the-art research and applications for treatment of cardiovascular disorders. Expert clinicians and researchers describe illustrative cases for each topic along with detailed discussions of current scientific understanding and its application in current disease management and treatment. Summaries, key teaching points, and illustrations are highlighted to facilitate quick recall and review. The book will be useful for cardiovascular clinicians in training, board preparation, or as a review for those already in clinical practice. Cardiovascular Genetics and Genomics in Clinical Practice features: Clinical case scenarios to illuminate the basic concepts of cardiovascular genetics and genomics as they are used in daily practice Explanation of fundamental concepts as a foundation for more in-depth understanding Detailed discussions of current scientific knowledge and clinical management The expertise of renowned clinician-scientists in the field Real practical insight for practice

Advanced Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Author: Philip Meneely,Matthew R. Willmann

Publisher: Oxford University Press

ISBN: N.A

Category: Medical

Page: 542

View: 8053

"With its unique integration of genetics and molecular biology, Advanced Genetic Analysis provides a broad survey of how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles and model organisms, the book goes on to explore the use of gene mutations and the analysis of gene expression and activity, before considering the interaction of genes during suppression and epistasis, and how we study gene networks." "Drawing on the latest experimental tools, including microarrays, RNAi, and bioinformatics approaches, Advanced Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research." --Book Jacket.

Methods in Genomic Neuroscience

Author: Hemin R. Chin,Steven O. Moldin

Publisher: CRC Press

ISBN: 1420038478

Category: Science

Page: 344

View: 5200

The past few years have witnessed extraordinary advances in molecular genetic techniques and the accumulation of structural genomics information and resources in both human and model organisms. With the development of new technologies and the availability of resources like the sequence of eukaryotic genomes, problems of a previously unthinkable scope are now being routinely solved in neuroscience and many other areas of biomedical research. The results of these studies, in turn, are having, and will continue to have, profound impact on experimental approaches and designs for manipulating genes, the genome, and model organisms as a means of gaining insights into nervous system functioning and complex behavior. Methods in Genomic Neuroscience provides newcomers and experienced researchers with a reference guide for applying powerful, state-of-the-art molecular genetic techniques to the study of neural and behavioral systems. It thereby provides a foundation by which data on gene expression and function may be used to develop new therapeutic strategies for brain diseases. Authored by researchers in the forefront of genomic neuroscience, the book addresses state-of-the-art tools and technologies for global analysis of genes influencing the nervous system and its disorders. An emphasis is placed on massively parallel approaches for analyzing the avalanche of data that is being generated from the full genomic sequence of humans and model systems. Specific topics include human sequence variation, methods for discovering disease vulnerability genes, gene-environmental interaction, gene expression analysis using DNA microarrays, random mutagenesis, gene trap approaches for studying brain development, neural stem cells, gene targeting, and gene delivery.

Essential Bioinformatics

Author: Jin Xiong

Publisher: Cambridge University Press

ISBN: 113945062X

Category: Science

Page: N.A

View: 1688

Essential Bioinformatics is a concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods. This balanced yet easily accessible text will be invaluable to students who do not have sophisticated computational backgrounds. Technical details of computational algorithms are explained with a minimum use of mathematical formulae; graphical illustrations are used in their place to aid understanding. The effective synthesis of existing literature as well as in-depth and up-to-date coverage of all key topics in bioinformatics make this an ideal textbook for all bioinformatics courses taken by life science students and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

Handbook of New Technologies for Genetic Improvement of Legumes

Author: P. B. Kirti

Publisher: CRC Press

ISBN: 9781439801352

Category: Technology & Engineering

Page: 680

View: 7284

A comprehensive and groundbreaking collection of ideas for plant improvement Most of the world’s supply of legumes is cultivated under adverse conditions that make this commercially important crop susceptible to the vagaries of nature and damaging stresses. Genetic manipulation has become a proven way for cultivators to battle these problems; but there has been a lack of reliable information on the practical aspects of this promising method. Handbook of New Technologies for Genetic Improvement of Legumes fills this void by providing a vast array of groundbreaking essays from some of the discipline’s most renowned experts. This unique collection is your single source for not only the most up-to-date accounts of genetic manipulation employed today, but also ideas for realistic and practical uses. Comprehensive in its approach, Handbook of New Technologies for Genetic Improvement of Legumes presents the latest research on all aspects of genetically modified legume production. With contributions from over 90 international experts, this eye-opening resource offers an in-depth exploration of key topics such as, genetic transformation technology, suppression-subtractive hybridization, c-DNA micro arrays, molecular mapping, tagging regulatory elements, and real-time PCR. Additionally, this text features a wealth of detailed references and informative tables to clearly explain pertinent data. Chapters in Handbook of New Technologies for Genetic Improvement of Legumes detail both family- and species-specific topics such as: • agrobacterium-mediated transformation in trifolium and medicago • biotechnological approaches to soybean improvement • transgenic approaches for enhancement of vitamin E • particle bombardment and SAAT approaches • agrobacterium tumefaciens-mediated transformation and in vitro regeneration • plant regeneration via organogenesis, somatic embryogenesis, and protoplast culture • somaclonal variation and its exploitation • cotyledonary node and embryo axes as explants • in planta transformation of pisum sativum l. • de novo regeneration protocol • reverse genetic approaches in medicago truncatula • tagging regulatory elements in plants • gene expression analysis with DNA array technology • advent of diverse DNA markers to decipher genome sequence polymorphism • defensins in legumes • legume-nematode interaction with reference to model legumes • and much, much more! Handbook of New Technologies for Genetic Improvement of Legumes is an invaluable resource for researchers and educators in the area of plant genetic manipulation and plant biotechnology as well as scientists, educators, and graduate students focusing on the genetic manipulation of legumes.

Genes & Genomes

A Changing Perspective

Author: Maxine Singer,Paul Berg

Publisher: University Science Books

ISBN: 9780935702170

Category: Science

Page: 929

View: 1626

This overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms emphasizes the experimental aspects of molecular genetics. It provides a complete introduction to both principles and methods.

Theories of Population Variation in Genes and Genomes

Author: Freddy B. Christiansen

Publisher: Princeton University Press

ISBN: 9780691133676

Category: Science

Page: 421

View: 6438

This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics

Essential Genetics

Author: Daniel L. Hartl

Publisher: Jones & Bartlett Publishers

ISBN: 1449686486

Category: Science

Page: 572

View: 1242

Updated throughout to reflect the latest discoveries in this fast-paced field, this Sixth Edition, provides an accessible, student-friendly introduction to modern genetics. Designed for the shorter, less comprehensive course, the Sixth Edition presents carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. It goes on to discuss the development and progression of genetics as a field of study within a societal and historical context. The Sixth Edition includes new learning objectives within each chapter which helps students identify what they should know as a result of their studying and highlights the skills they should acquire through various practice problems.