Genetics

Author: Hartl

Publisher: Jones & Bartlett Learning

ISBN: 1284156710

Category: Medical

Page: 830

View: 8852

Genetics: Analysis of Genes and Genomes continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provides students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation.

Analysis of Genes and Genomes

Author: Richard J. Reece

Publisher: John Wiley & Sons Incorporated

ISBN: 9780470777817

Category: Medical

Page: 520

View: 6556

All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Strong emphasis is placed on the latest, post genomic technologies including DNA macro and microarrays, genome-wide two hybrid analysis, proteomics and bioinformatics. An example driven past-to-present approach to allow the experiments of today to be placed in an historical context Associated website including updates, additional content and illusions

Student Solutions Manual and Supplemental Problems to Accompany Genetics: Analysis of Genes and Genomes

Author: Daniel L. Hartl,Maryellen Ruvolo

Publisher: Jones & Bartlett Publishers

ISBN: 1449644708

Category: Science

Page: 392

View: 364

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Genetics

Author: Daniel L. Hartl,Maryellen Ruvolo

Publisher: Jones & Bartlett Publishers

ISBN: 1449671128

Category: Science

Page: 392

View: 7434

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Author: Philip Meneely

Publisher: Oxford University Press, USA

ISBN: 0199651817

Category: Medical

Page: 580

View: 9490

How do we know what role a particular gene has? How do some genes control the expression of others? How do genes interact to form gene networks? With its unique integration of genetics and molecular biology, Genetic Analysis probes fascinating questions such as these, detailing how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles, model organisms, and epigenetics, the book goes on to explorethe use of gene mutations and the analysis of gene expression and activity. A discussion of the genetic structure of natural populations follows, before the interaction of genes during suppression and epistasis, how we study gene networks, and personalized genomics are considered. Drawing on the latest experimental tools, including microarrays, RNAi screens, and bioinformatics approaches, Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight. We are in an age where, despite knowing so much about biological systems, we are just beginning to realise how much more there is still to understand. Genetic Analysis is the ideal guide to how we can use the awesome power of molecular genetics to further our understanding. Online Resource Centre: The Online Resource Centre to accompany Genetic Analysis features the following resources for teachers and students: For students: * Topical updates - key updates on topics or tools presented in the book, to keep you up-to-date with the latest developments in the field. * Additional case studies and text boxes to complement and add to those found in the book. * Practice problems, to test the reader's knowledge of the concepts presented, and help to master them. For registered adopters ofthe book: * Figures from the book in electronic format, ready to download. * Journal clubs - suggested papers and discussion questions linked to topics covered in the book.

From Genes to Genomes

Concepts and Applications of DNA Technology

Author: Jeremy W. Dale,Malcolm von Schantz,Nick Plant

Publisher: John Wiley & Sons

ISBN: 0470683864

Category: Science

Page: 386

View: 8263

Rapid advances in a collection of techniques referred to as gene technology, genetic engineering, recombinant DNA technology and gene cloning have pushed molecular biology to the forefront of the biological sciences.

Genetics

From Genes to Genomes

Author: Leland Hartwell

Publisher: McGraw-Hill Higher Education

ISBN: 0077515099

Category: Science

Page: 816

View: 7649

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.

Modern Genetic Analysis

Integrating Genes and Genomes

Author: Anthony J.F. Griffiths

Publisher: Macmillan

ISBN: 9780716743828

Category: Science

Page: 736

View: 4097

Part 1: Fundamentals of gene structure, function, and transmission; Genetics and the organism; The structure of genes and genomes; Gene function; The transmission of DNA at cell division; The inheritance of single-gene differences; Genetic recombination in eukaryotes; Recombination in bacteria and their viruses. Part 2: Methods of genetic manipulation; Recombinant DNA and genetic engineering; Genomics; Gene mutation: origins and repair processes; Chromosome mutations; Mutation dissection. Part 3: Systems genetics: from gene to phenotype; Regulation of hene transciption; From gene to phenotype; Regulation of cell number: normal and cancer cells; The genetic basis of development. Part 4: Genetic analysis of populations; Population genetics; Quantitative genetics; Evolutionary genetics.

Genetics

Genes, Genomes, and Evolution

Author: Philip Meneely,Rachel Dawes Hoang,Katherine Heston,Iruka N. Okeke

Publisher: Oxford University Press

ISBN: 019879536X

Category: Science

Page: 740

View: 7413

Recent advances that allow scientists to quickly and accurately sequence a genome have revolutionized our view of the structure and function of genes as well as our understanding of evolution. A new era of genetics is underway, one that allows us to fully embrace Dobzhansky's famous statement that "Nothing in biology makes sense except in the light of evolution". Genetics: Genes, Genomes, and Evolution presents the fundamental principles of genetics and molecular biology from an evolutionary perspective as informed by genome analysis. By using what has been learned from the analyses of bacterial and eukaryotic genomes as its basis, the book unites evolution, genomics, and genetics in one narrative approach. Genomic analysis is inherently both molecular and evolutionary, and every chapter is approached from this unified perspective. Similarly, genomic studies have provided a deeper appreciation of the profound relationships between all organisms - something reflected in the book's integrated discussion of bacterial and eukaryotic evolution, genetics and genomics. It is an approach that provides students with a uniquely flexible and contemporary view of genetics, genomics, and evolution. Online Resource Centre: - Video tutorials: a series of videos that provide deeper, step-by-step explanations of a range of topics featured in the text. - Flashcards: electronic flashcards covering the key terms from the text. For registered adopters of the text: - Digital image library: Includes electronic files in PowerPoint format of every illustration, photo, graph and table from the text - Lecture notes: Editable lecture notes in PowerPoint format for each chapter help make preparing lectures faster and easier than ever. Each chapter's presentation includes a succinct outline of key concepts, and incorporates the graphics from the chapter - Library of exam-style questions: a suite of questions from which you can pick potential assignments and exams. - Test bank of multiple-choice questions: a ready-made electronic testing resource that can be customized by lecturers and delivered via their institution's virtual learning environment. - Solutions to all questions featured in the book: solutions written by the authors help make the grading of homework assignments easier. - Journal Clubs: a series of questions that guide your students through the reading and interpretation of a research paper that relates to the subject matter of a given chapter. Each Journal club includes model answers for lecturers. - Instructor's guide: The instructor's guide discusses the educational approach taken by Genetics: Genes, Genomes, and Evolution in more detail, why this approach has been taken, what benefits it offers, and how it can be adopted in your class.

Adaptive Evolution of Genes and Genomes

Author: Austin L. Hughes

Publisher: Oxford University Press, USA

ISBN: 9780195116267

Category: Science

Page: 270

View: 4432

This valuable book thoroughly examines adaptive evolution at the DNA level while taking a comprehensive look at the research being done in the area. It presents useful cases where signals of adaptive evolution are detected through neutral molecular evolution, providing a powerful strategy for testing the Darwinian hypothesis of natural selection. By bridging the gap between research on molecular and phenotype evolution and contributing to the unification of the biological sciences, this book will especially appeal to researchers and graduate students in the field of evolutionary biology. Also, with its focus on particular protein molecules and on specific domains of these proteins, it will benefit a wider audience of both evolutionary and functional biologists.

Advanced Genetic Analysis

Finding Meaning in a Genome

Author: R. Scott Hawley,Michelle Walker

Publisher: John Wiley & Sons

ISBN: 1444313088

Category: Science

Page: 256

View: 641

Advanced Genetic Analysis brings a state-of-the-art, exciting new approach to genetic analysis. Focusing on the underlying principles of modern genetic analysis, this book provides the 'how' and 'why' of the essential analytical tools needed. The author's vibrant, accessible style provides an easy guide to difficult genetic concepts, from mutation and gene function to gene mapping and chromosome segregation. Throughout, a balanced range of model organisms and timely examples are used to illustrate the theoretical basics. Basic principles - Focuses students attention on the 'how' and 'why' of the essential analytical tools. Vibrant, accessible style provides an easy guide through difficult genetic concepts and techniques. Text boxes highlight key questions and timely examples. Boxes of key information in each chapter, chapter summaries and extensive references - prompt the student to synthesise and reinforce the chapter material. Special reference section addressing a range of model organisms to help provide a particularly relevant context for students' research interests.

Molecular Biology

Author: Burton E. Tropp

Publisher: Jones & Bartlett Publishers

ISBN: 0763786632

Category: Science

Page: 1097

View: 2208

"Molecular Biology: Genes to Proteins is a guide through the basic molecular processes and genetic phenomena of both prokaryotic and eukaryotic cells. Written for the undergraduate and first year graduate students within molecular biology or molecular genetics, the text has been updated with the latest data in the field. It incorporates a biochemical approach as well as a discovery approach that provides historical and experimental information within the context of the narrative."--Publisher.

Advanced Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Author: Philip Meneely,Matthew R. Willmann

Publisher: Oxford University Press

ISBN: N.A

Category: Medical

Page: 542

View: 3975

"With its unique integration of genetics and molecular biology, Advanced Genetic Analysis provides a broad survey of how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles and model organisms, the book goes on to explore the use of gene mutations and the analysis of gene expression and activity, before considering the interaction of genes during suppression and epistasis, and how we study gene networks." "Drawing on the latest experimental tools, including microarrays, RNAi, and bioinformatics approaches, Advanced Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research." --Book Jacket.

Genes & Genomes

A Changing Perspective

Author: Maxine Singer,Paul Berg

Publisher: University Science Books

ISBN: 9780935702170

Category: Science

Page: 929

View: 4222

This overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms emphasizes the experimental aspects of molecular genetics. It provides a complete introduction to both principles and methods.

Human Genes and Genomes

Science, Health, Society

Author: Leon E. Rosenberg,Diane Drobnis Rosenberg

Publisher: Academic Press

ISBN: 0123852137

Category: Science

Page: 446

View: 1529

In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics

Linkage Disequilibrium and Association Mapping

Analysis and Applications

Author: Andrew Collins

Publisher: Springer Science & Business Media

ISBN: 1597453897

Category: Science

Page: 255

View: 6840

As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In "Linkage Disequilibrium and Association Mapping: Analysis and Applications," scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. The volume comprises four general sections: the first presents an overview and historical basis of the subject. The second section considers the developing methodology and recent findings from studies which have characterized the genome-wide linkage disequilibrium structure in enormous detail. The following section examines all aspects of disease association mapping methodology, and the final two chapters review the early successes in mapping genes involved in two of the most important human diseases: asthma and type 2 diabetes.

Foundations of Comparative Genomics

Author: Arcady R. Mushegian

Publisher: Elsevier

ISBN: 9780080546094

Category: Science

Page: 280

View: 9923

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. Presents an historic overview of genome biology and its achievements Includes topics not covered in other books such as minimal and ancestral genomes Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level Critically reviews horizontal gene transfer and other contentious issues Covers comparative virology as a somewhat overlooked foundation of modern genome science