Fractals in Molecular Biophysics

Author: T. Gregory Dewey

Publisher: Oxford University Press

ISBN: 9780195359183

Category: Science

Page: 288

View: 2687

Historically, science has sought to reduce complex problems to their simplest components, but more recently it has recognized the merit of studying complex phenomena in situ. Fractal geometry is one such appealing approach, and this book discusses its application to complex problems in molecular biophysics. The book provides a detailed, unified treatment of fractal aspects of protein and structure dynamics, fractal reaction kinetics in biochemical systems, sequence correlations in DNA and proteins, and descriptors of chaos in enzymatic systems. In an area that has been slow to acknowledge the use of fractals, this is an important addition to the literature, offering a glimpse of the wealth of possible applications to complex problems.

Biophysical Chemistry of Fractal Structures and Processes in Environmental Systems

Author: Nicola Senesi,Kevin J. Wilkinson

Publisher: John Wiley & Sons

ISBN: 0470511192

Category: Science

Page: 340

View: 7600

This book aims to provide the scientific community with a novel and valuable approach based on fractal geometry concepts on the important properties and processes of diverse environmental systems. The interpretation of complex environmental systems using modern fractal approaches is compared and contrasted with the more classical approaches. The book will provide the fundamental knowledge necessary for solving practical environmental problems. Furthermore, it examinea how the fractal approach has been applied in order to understand the structure and reactivity of natural, environmental systems including flocs, sediments, soils, microorganisms and humic substances.

Fractals in Chemistry, Geochemistry, and Biophysics

An Introduction

Author: K.S. Birdi

Publisher: Springer Science & Business Media

ISBN: 1489911243

Category: Science

Page: 264

View: 1509

In this introductory text, Dr. Birdi demonstrates experimental methods and analyses of fractal dimensions in natural processes. In addition to a general overview, he discusses in detail problems in the fields of chemistry, geochemistry, and biophysics. Both students and professionals with a minimum of mathematics or physical science training will learn to find and model shapes and patterns from their own everyday observations.

Molecular Orbital Calculations for Biological Systems

Author: Anne-Marie Sapse

Publisher: Oxford University Press

ISBN: 9780195356847

Category: Medical

Page: 256

View: 1108

Molecular Orbital Calculations for Biological Systems is a hands-on guide to computational quantum chemistry and its applications in organic chemistry, biochemistry, and molecular biology. With improvements in software, molecular modeling techniques are now becoming widely available; they are increasingly used to complement experimental results, saving significant amounts of lab time. Common applications include pharmaceutical research and development; for example, ab initio and semi-empirical methods are playing important roles in peptide investigations and in drug design. The opening chapters provide an introduction for the non-quantum chemist to the basic quantum chemistry methods, ab initio, semi-empirical, and density functionals, as well as to one of the main families of computer programs, the Gaussian series. The second part then describes current research which applies quantum chemistry methods to such biological systems as amino acids, peptides, and anti-cancer drugs. Throughout the authors seek to encourage biochemists to discover aspects of their own research which might benefit from computational work. They also show that the methods are accessible to researchers from a wide range of mathematical backgrounds. Combining concise introductions with practical advice, this volume will be an invaluable tool for research on biological systems.

Molecular Orbital Calculations for Biological Systems

Author: Anne-Marie Sapse

Publisher: Oxford University Press on Demand

ISBN: 0195098730

Category: Medical

Page: 233

View: 1331

Molecular Orbital Calculations for Biological Systems is a hands-on guide to computational quantum chemistry and its applications in organic chemistry, biochemistry, and molecular biology. With improvements in software, molecular modeling techniques are now becoming widely available; they are increasingly used to complement experimental results, saving significant amounts of lab time. Common applications include pharmaceutical research and development; for example, ab initio and semi-empirical methods are playing important roles in peptide investigations and in drug design. The opening chapters provide an introduction for the non-quantum chemist to the basic quantum chemistry methods, ab initio, semi-empirical, and density functionals, as well as to one of the main families of computer programs, the Gaussian series. The second part then describes current research which applies quantum chemistry methods to such biological systems as amino acids, peptides, and anti-cancer drugs. Throughout the authors seek to encourage biochemists to discover aspects of their own research which might benefit from computational work. They also show that the methods are accessible to researchers from a wide range of mathematical backgrounds. Combining concise introductions with practical advice, this volume will be an invaluable tool for research on biological systems.

Chemical Biophysics

Quantitative Analysis of Cellular Systems

Author: Daniel A. Beard,Hong Qian

Publisher: Cambridge University Press

ISBN: 1139470078

Category: Technology & Engineering

Page: N.A

View: 9950

Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.

Introduction to Molecular Biophysics

Author: Jack A. Tuszynski,Michal Kurzynski

Publisher: CRC Press

ISBN: 9780203009963

Category: Science

Page: 584

View: 7186

Molecular biophysics is a rapidly growing field of research that plays an important role in elucidating the mysteries of life's molecules and their assemblies, as well as the relationship between their structure and function. Introduction to Molecular Biophysics fills an existing gap in the literature on this subject by providing the reader with the modern theoretical tools needed to understand life processes from a physical viewpoint. The authors review numerous topics of relevance to biophysics, including peptide chains, DNA structure and function, cytoplasm, membranes, and motor proteins. Each chapter is richly illustrated and contains numerous examples, references, and problems that make this book useful as both an inclusive reference work and textbook.

Fundamental Concepts in Biophysics

Author: Thomas Jue

Publisher: Springer Science & Business Media

ISBN: 1597453978

Category: Science

Page: 248

View: 3204

In the first volume, Fundamental Concepts in Biophysics, the authors lay down a foundation for biophysics study. Rajiv Singh opens the book by pointing to the central importance of “Mathematical Methods in Biophysics”. William Fink follows with a discussion on “Quantum Mechanics Basic to Biophysical Methods”. Together, these two chapters establish some of the principles of mathematical physics underlying many biophysics techniques. Because computer modeling forms an intricate part of biophysics research, Subhadip Raychaudhuri and colleagues introduce the use of computer modeling in “Computational Modeling of Receptor–Ligand Binding and Cellular Signaling Processes”. Yin Yeh and coworkers bring to the reader’s attention the physical basis underlying the common use of fluorescence spectroscopy in biomedical research in their chapter “Fluorescence Spectroscopy”. Electrophysiologists have also applied biophysics techniques in the study of membrane proteins, and Tsung-Yu Chen et al. explore stochastic processes of ion transport in their “Electrophysiological Measurements of Membrane Proteins”. Michael Saxton takes up a key biophysics question about particle distribution and behavior in systems with spatial or temporal inhomogeneity in his chapter “Single–Particle Tracking”. Finally, in “NMR Measurement of Biomolecule Diffusion”, Thomas Jue explains how magnetic resonance techniques can map biomolecule diffusion in the cell to a theory of respiratory control. This book thus launches the Handbook of Modern Biophysics series and sets up for the reader some of the fundamental concepts underpinning the biophysics issues to be presented in future volumes.

Hadron models and related New Energy issues

Author: Florentin Smarandache,V. Christianto

Publisher: Infinite Study

ISBN: 1599730421

Category: Cold fusion

Page: 454

View: 5297

The present book covers a wide-range of issues from alternative hadron models to their likely implications to New Energy research, including alternative interpretation of low-energy reaction (coldfusion) phenomena.The authors explored some new approaches to describe novel phenomena in particle physics. M Pitkanen introduces his nuclear string hypothesis derived from his Topological Geometrodynamics theory, while E. Goldfain discusses a number of nonlinear dynamics methods, including bifurcation, pattern formation (complex Ginzburg-Landau equation) to describe elementary particle masses. Fu Yuhua discusses a plausible method for prediction of phenomena related to New Energy development.F. Smarandache discusses his unmatter hypothesis, and A. Yefremov et al. discuss Yang-Mills field from Quaternion Space Geometry. Diego Rapoport discusses link between Torsion fields and Hadronic Mechanic.A.H. Phillips discusses semiconductor nanodevices, while V. and A. Boju discuss Digital Discrete and Combinatorial methods and their likely implications to New Energy research. Pavel Pintr et al. describe planetary orbit distance from modified Schrodinger equation, and M. Pereira discusses his new Hypergeometrical description of Standard Model of elementary particles.The present volume will be suitable for researchers interested in New Energy issues, in particular their link with alternative hadron models and interpretation.While some of these discussions may be found a bit too theoretical, our view is that once these phenomena can be put into rigorous theoretical framework, thereafter more 'open-minded' physicists may be more ready to consider these New Energy methods more seriously. Our basic proposition in the present book is that considering these new theoretical insights, one can expect there are new methods to generate New Energy technologies which are clearly within reach of human knowledge in the coming years.

Integrated Molecular and Cellular Biophysics

Author: Valerica Raicu,Aurel Popescu

Publisher: Springer Science & Business Media

ISBN: 1402082681

Category: Science

Page: 250

View: 6153

Biophysics represents perhaps one of the best examples of interdisciplinary research areas, where concepts and methods from disciplines such as physics, biology, b- chemistry, colloid chemistry, and physiology are integrated. It is by no means a new ?eld of study and has actually been around, initially as quantitative physiology and partly as colloid science, for over a hundred years. For a long time, biophysics has been taught and practiced as a research discipline mostly in medical schools and life sciences departments, and excellent biophysics textbooks have been published that are targeted at a biologically literate audience. With a few exceptions, it is only relatively recently that biophysics has started to be recognized as a physical science and integrated into physics departments’ curr- ula, sometimes under the new name of biological physics. In this period of cryst- lization and possible rede?nition of biophysics, there still exists some uncertainty as to what biophysics might actually represent. A particular tendency among phy- cists is to associate biophysics research with the development of powerful new te- niques that should eventually be used not by physicists to study physical processes in living matter, but by biologists in their biological investigations. There is value in that judgment, and excellent books have been published that introduce the int- ested reader to the use of physical principles for the development of new methods of investigation in life sciences.

Fractal Physiology

Author: James B Bassingthwaighte,Larry S Liebovitch,Bruce J. West

Publisher: Springer

ISBN: 1461475724

Category: Medical

Page: 384

View: 7230

I know that most men, including those at ease with the problems of the greatest complexity, can seldom accept even the simplest and most obvious truth if it be such as would oblige them to admit the falsity of conclusions which they have delighted in explaining to colleagues, which they have proudly taught to others, and which they have woven, thread by thread, into the fabric of their lives. Joseph Ford quoting Tolstoy (Gleick, 1987) We are used to thinking that natural objects have a certain form and that this form is determined by a characteristic scale. If we magnify the object beyond this scale, no new features are revealed. To correctly measure the properties of the object, such as length, area, or volume, we measure it at a resolution finer than the characteristic scale of the object. We expect that the value we measure has a unique value for the object. This simple idea is the basis of the calculus, Euclidean geometry, and the theory of measurement. However, Mandelbrot (1977, 1983) brought to the world's attention that many natural objects simply do not have this preconceived form. Many of the structures in space and processes in time of living things have a very different form. Living things have structures in space and fluctuations in time that cannot be characterized by one spatial or temporal scale. They extend over many spatial or temporal scales.

The Rainbow and the Worm

The Physics of Organisms

Author: Mae-Wan Ho

Publisher: World Scientific

ISBN: 9812832599

Category: Science

Page: 380

View: 6779

This highly unusual book began as a serious inquiry into Schr”dinger's question, ?What is life??, and as a celebration of life itself. It takes the reader on a voyage of discovery through many areas of contemporary physics, from non-equilibrium thermodynamics and quantum optics to liquid crystals and fractals, all necessary for illuminating the problem of life. In the process, the reader is treated to a rare and exquisite view of the organism, gaining novel insights not only into the physics, but also into ?the poetry and meaning of being alive.?This much-enlarged third edition includes new findings on the central role of biological water in organizing living processes; it also completes the author's novel theory of the organism and its applications in ecology, physiology and brain science.

Molecular Biophysics for the Life Sciences

Author: Norma M. Allewell,Linda O. Narhi,Ivan Rayment

Publisher: Springer Science & Business Media

ISBN: 1461485487

Category: Science

Page: 397

View: 884

This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.

A Guide to Monte Carlo Simulations in Statistical Physics

Author: David P. Landau,Kurt Binder

Publisher: Cambridge University Press

ISBN: 1316062635

Category: Science

Page: N.A

View: 3255

Dealing with all aspects of Monte Carlo simulation of complex physical systems encountered in condensed-matter physics and statistical mechanics, this book provides an introduction to computer simulations in physics. This fourth edition contains extensive new material describing numerous powerful algorithms not covered in previous editions, in some cases representing new developments that have only recently appeared. Older methodologies whose impact was previously unclear or unappreciated are also introduced, in addition to many small revisions that bring the text and cited literature up to date. This edition also introduces the use of petascale computing facilities in the Monte Carlo arena. Throughout the book there are many applications, examples, recipes, case studies, and exercises to help the reader understand the material. It is ideal for graduate students and researchers, both in academia and industry, who want to learn techniques that have become a third tool of physical science, complementing experiment and analytical theory.

Growth Patterns in Physical Sciences and Biology

Author: Jaun-Manuel Garcia-Ruiz,Enrique Louis,P. Meakin,Leonard M. Sander

Publisher: Springer Science & Business Media

ISBN: 1461528526

Category: Science

Page: 429

View: 4945

During the past decade interest in the formation of complex disorderly patterns far from equilibrium has grown rapidly. This interest has been stim ulated by the development of new approaches (based primarily on fractal geometry) to the quantitative description of complex structures, increased understanding of non-linear phenomena and the introduction of a variety of models (such as the diffusion-limited aggregation model) that provide paradigms for non-equilibrium growth phenomena. Advances in computer technology have played a crucial role in both the experimental and theoret ical aspects of this enterprise. Substantial progress has been made towards the development of comprehensive understanding of non-equilibrium growth phenomena but most of our current understanding is based on simple com puter models. Pattern formation processes are important in almost all areas of science and technology, and, clearly, pattern growth pervades biology. Very often remarkably similar patterns are found in quite diverse systems. In some case (dielectric breakdown, electrodeposition, fluid-fluid displacement in porous media, dissolution patterns and random dendritic growth for example) the underlying causes of this similarity is quite well understood. In other cases (vascular trees, nerve cells and river networks for example) we do not yet know if a fundamental relationship exists between the mechanisms leading the formation of these structures.

Biophysics

A Physiological Approach

Author: Patrick F. Dillon

Publisher: Cambridge University Press

ISBN: 1107001447

Category: Science

Page: 298

View: 9428

Explains the quantitative basis of human life to life science students, with examples drawn from contemporary physiology, genetics and nanobiology.

The Journal of Cell Biology

Author: N.A

Publisher: N.A

ISBN: N.A

Category: Cells

Page: N.A

View: 7516

No. 2, pt. 2 of November issue each year from v. 19-47; 1963-70 and v. 55- 1972- contain the Abstracts of papers presented at the annual meeting of the American Society for Cell Biology, 3d-10th; 1963-70 and 12th- 1972- .