Foundations of Chemical Biology

Author: Christopher M. Dobson,Juliet A. Gerrard,Andrew J. Pratt

Publisher: Oxford University Press, USA

ISBN: 9780199248995

Category: Science

Page: 97

View: 4006

This book introduces the fundamental chemistry of the molecules that are essential to all cells, covering amino acids and sugar phosphate derivatives, and the macromolecules derived from them. In such a short text it is not possible to provide a comprehensive account of such molecules; instead it covers important concepts concerning their intrinsic chemistry. The aim is to provide the fundamental ideas relating to the chemistry of life that can then be applied to more advanced aspects of chemical biology.

The Physical Basis of Biochemistry

The Foundations of Molecular Biophysics

Author: Peter R. Bergethon

Publisher: Springer Science & Business Media

ISBN: 9781441963246

Category: Science

Page: 949

View: 7789

Biological chemistry has changed since the completion of the human genome project. There is a renewed interest and market for individuals trained in biophysical chemistry and molecular biophysics. The Physical Basis of Biochemistry, Second Edition, emphasizes the interdisciplinary nature of biophysical chemistry by incorporating the quantitative perspective of the physical sciences without sacrificing the complexity and diversity of the biological systems, applies physical and chemical principles to the understanding of the biology of cells and explores the explosive developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies that have occurred in the past seven years. The book features problem sets and examples, clear illustrations, and extensive appendixes that provide additional information on related topics in mathematics, physics and chemistry.

The Evolutionary Foundations of Economics

Author: Kurt Dopfer

Publisher: Cambridge University Press

ISBN: 9781139443234

Category: Business & Economics

Page: N.A

View: 4676

It is widely recognised that mainstream economics has failed to translate micro consistently into macro economics and to provide endogenous explanations for the continual changes in the economic system. Since the early 1980s, a growing number of economists have been trying to provide answers to these two key questions by applying an evolutionary approach. This new departure has yielded a rich literature with enormous variety, but the unifying principles connecting the various ideas and views presented are, as yet, not apparent. This 2005 volume brings together fifteen original articles from scholars - each of whom has made a significant contribution to the field - in their common effort to reconstruct economics as an evolutionary science. Using meso economics as an analytical entity to bridge micro and macro economics as well as static and dynamic realms, a unified economic theory emerges.

Foundations of Structural Biology

Author: Leonard J. Banaszak

Publisher: Elsevier

ISBN: 9780080521848

Category: Science

Page: 168

View: 7911

Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features * Explains how to use coordinate databases and atomic coordinates of biological macromolecules * Teaches the skills of stereoviewing * Contains computer-generated stereographics * Describes the principles of symmetry and handedness in proteins and DNA * Introduces metal and lipid binding proteins and DNA-protein interactions * Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions

Chemistry for the Biosciences

The Essential Concepts

Author: Jonathan Crowe,Tony Bradshaw

Publisher: Oxford University Press

ISBN: 0199570876

Category: Education

Page: 678

View: 2168

Focuses on the key chemical concepts which students of the biosciences need to understand, making the scope of the book directly relevant to the target audience.

Proceedings of the 8th International Conference on Foundations of Computer-Aided Process Design

Author: N.A

Publisher: Elsevier

ISBN: 0444634428

Category: Technology & Engineering

Page: 840

View: 3691

This volume collects together the presentations at the Eighth International Conference on Foundations of Computer-Aided Process Design, FOCAPD-2014, an event that brings together researchers, educators, and practitioners to identify new challenges and opportunities for process and product design. The chemical industry is currently entering a new phase of rapid evolution. The availability of low-cost feedstocks from natural gas is causing renewed investment in basic chemicals in the OECD, while societal pressures for sustainability and energy security continue to be key drivers in technology development and product selection. This dynamic environment creates opportunities to launch new products and processes and to demonstrate new methodologies for innovation, synthesis and design. FOCAPD-2014 fosters constructive interaction among thought leaders from academia, industry, and government and provides a showcase for the latest research in product and process design. Focuses exclusively on the fundamentals and applications of computer-aided design for the process industries. Provides a fully archival and indexed record of the FOCAPD14 conference Aligns the FOCAPD series with the ESCAPE and PSE series

Foundations of Bioenergetics

Author: Harold Morowitz

Publisher: Elsevier

ISBN: 0323154050

Category: Science

Page: 364

View: 2132

Foundations of Bioenergetics provides an introduction to the physical foundations of bioenergetics and the methods of applying these constructs to biological problems. It combines parts of thermal physics, biochemistry, ecology, and cellular and organismic biology into a single coherent work. Much of the material in this volume comes from ""Entropy for Biologists,"" an introductory thermodynamics book aimed particularly at life scientists. Some of the topics originally appeared in the monograph ""Energy Flow in Biology."" The current volume expands on that material with respect to biological applications and attempts to bridge the gap between physics and biology. The book explains basic concepts such as energy, temperature, the second law of thermodynamics, entropy, information theory, and statistical mechanics. It discusses the relations between thermodynamics and statistical mechanics, free-energy functions, radiant energy, the free energy of cells and tissue, chemical kinetics, and cyclic flows. It examines the relationships between energy flows and biological processes; applications of the concepts of Gibbs free energy, chemical potential, and activity; and measurements of temperature, energy, and thermochemical quantities. The book also includes chapters that deal with irreversible dynamics, irreversible theory, and osmotic flow.

Foundations of Mathematical Biology

Cellular Systems

Author: Robert J. Rosen

Publisher: Elsevier

ISBN: 1483271846

Category: Science

Page: 348

View: 5158

Foundations of Mathematical Biology, Volume II: Cellular Systems describes the properties of cellular systems and their relationship to the development of multicellular organisms. This volume is composed of five chapters that present the mathematical tools applied in evaluating these systems. Chapters 1 illustrates the use of continuous time systems to examine the relationship between the properties of individual cells and the general problems of morphogenesis in developing systems, specifically how these properties could manifest themselves in morphological terms. Chapter 2 demonstrates the systems of rate equations or first-order differential equations to deal with the regulation of individual chemical processes and sequences of such processes, at both the genetic and metabolic levels. Chapter 3 discusses the application of the theory of automata to the evaluation of the concept and principles of embryology, while Chapter 4 presents some relational cell models to study the metabolism-repair cellular systems. Chapter 5 looks into the concept and systems of a compartment. This book will prove useful to mathematical and cell biologists and researchers.

Essentials of Chemical Biology

Structure and Dynamics of Biological Macromolecules

Author: Andrew D. Miller,Julian Tanner

Publisher: John Wiley & Sons

ISBN: 1118687833

Category: Science

Page: 592

View: 3193

“This excellent work fills the need for an upper-levelgraduate course resource that examines the latest biochemical,biophysical, and molecular biological methods for analyzing thestructures and physical properties of biomolecules… Thisreviewer showed [the book] to several of his senior graduatestudents, and they unanimously gave the book rave reviews.Summing Up: Highly recommended…” CHOICE Chemical biology is a rapidly developing branch of chemistry,which sets out to understand the way biology works at the molecularlevel. Fundamental to chemical biology is a detailed understandingof the syntheses, structures and behaviours of biologicalmacromolecules and macromolecular lipid assemblies that togetherrepresent the primary constituents of all cells and all organisms.The subject area of chemical biology bridges many differentdisciplines and is fast becoming an integral part of academic andcommercial research. This textbook is designed specifically as a key teachingresource for chemical biology that is intended to build onfoundations lain down by introductory physical and organicchemistry courses. This book is an invaluable text for advancedundergraduates taking biological, bioorganic, organic andstructural chemistry courses. It is also of interest to biochemistsand molecular biologists, as well as professionals within themedical and pharmaceutical industry. Key Features: A comprehensive introduction to this dynamic area of chemistry,which will equip chemists for the task of understanding andstudying the underlying principles behind the functioning ofbiological macro molecules, macromolecular lipid assemblies andcells. Covers many basic concepts and ideas associated with the studyof the interface between chemistry and biology. Includes pedagogical features such as: key examples, glossaryof equations, further reading and links to websites. Clearly written and richly illustrated in fullcolour.

Foundations of Biophilosophy

Author: Martin Mahner,Mario Bunge,Professor Mario Bunge

Publisher: Springer Science & Business Media

ISBN: 9783540618386

Category: Medical

Page: 423

View: 4492

Over the past three decades, the philosophy of biology has emerged from the shadow of the philosophy of physics to become a respectable and thriving philosophical subdiscipline. In their book, the authors take a fresh look at the life sciences and their philosophy from a strictly realist and emergentist-naturalist perspective. They outline a unified and science-oriented philosophical framework that enables them to clarify many foundational and philosophical issues in biology. Thus, this book should be of interest to both life scientists and philosophers and is suitable as a textbook for courses at the advanced levels as well as for independent study.


Author: W. Hoppe,W. Lohmann,H. Markl,H. Ziegler

Publisher: Springer Science & Business Media

ISBN: 3642688772

Category: Science

Page: 941

View: 521

What is biophysics? As with all subjects which straddle traditional boundaries between fields, it eludes a precise definition. Furthermore, it is impossible to do biophysics without having a certain foundation of knowledge in biology, physics, physical chemistry, chemistry and biochemistry. One approach to a biophysics textbook would be to refer the student to the literature of these neighboring fields, and to leave the selection of the appropriate supplementary material up to the student. The editors of this volume are of the opinion that it is more useful and less time-consuming to present a selection of the supplementary knowledge, in concentrated form, together with the subject matter specific to biophysics. The reader will thus find in this book introductions to such subjects as the structure and function of the cell, the chemical structure of biogenic macromolecules, and even theoretical chemistry. What, indeed, is biophysics? Must we consider it to include physiology, electromedicine, radiation medicine, etc. ? The field has evolved continuously in recent years. Molecular understanding oflife processes has come more and more to the fore. Just as the field of molecular physics has developed to describe structures and processes in the realm of non-living systems, there has been a corresponding development of molecular biophysics.

Systems Biology

Philosophical Foundations

Author: Fred Boogerd,Frank J. Bruggeman,Jan-Hendrik S. Hofmeyr,H.V. Westerhoff

Publisher: Elsevier

ISBN: 9780080475271

Category: Computers

Page: 360

View: 1873

Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies. * Answers the question of what distinguishes the living from the non-living * An in-depth look to a vigorous and expanding discipline, from molecule to system * Explores the region between individual components and the system

Problems of Cell Permeability

International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences

Author: A.S. Troshin

Publisher: Elsevier

ISBN: 1483222616

Category: Science

Page: 564

View: 7215

Modern Trends in Physiological Science, Volume 26: Problem of Cell Permeability covers expounded sorptional theory of cell permerbeality. The problem of cell permeability deals with the questions connected with the laws of the entrance of substances from the surrounding medium into cells and the excretion from the latter of the products of intracellular metabolism. This book is composed of 12 chapters and begins with an overview of the chemical composition and structure of cell membrane, as well as the membrane theory of cell permeability. The next chapters treat the issues of cell’s osmometric activity and the physico-chemical properties of protoplasm as a system of coacervates. Considerable chapters are devoted to cell permeability for various substrates, such as non-electrolytes, organic acids, vital dyes, and mineral substances. The concluding chapters discuss the relationship between metabolism and cell permeability; the bioelectric properties of cell; and the protective action of non-electrolytes against live matter damage caused by dilute saline media. This book will be of value to cell biologists, biochemists, and research workers in cell permeability.

Molecules in Physics, Chemistry, and Biology

Electronic Structure and Chemical Reactivity

Author: Jean Maruani

Publisher: Springer Science & Business Media

ISBN: 9789027725981

Category: Science

Page: 460

View: 8286

Volume 1: General Introduction to Molecular Sciences Volume 2: Physical Aspects of Molecular Systems Volume 3: Electronic Structure and Chemical Reactivity Volume 4: Molecular Phenomena in Biological Sciences

Cognitive Foundations of Natural History

Towards an Anthropology of Science

Author: Scott Atran

Publisher: Cambridge University Press

ISBN: 9780521438711

Category: Science

Page: 360

View: 3137

Inspired by a debate between Noam Chomsky and Jean Piaget, this work traces the development of natural history from Aristotle to Darwin, and demonstrates how the science of plants and animals has emerged from the common conceptions of folkbiology.

Foundations of Factor Analysis, Second Edition

Author: Stanley A Mulaik

Publisher: CRC Press

ISBN: 1420099817

Category: Mathematics

Page: 548

View: 7878

Providing a practical, thorough understanding of how factor analysis works, Foundations of Factor Analysis, Second Edition discusses the assumptions underlying the equations and procedures of this method. It also explains the options in commercial computer programs for performing factor analysis and structural equation modeling. This long-awaited edition takes into account the various developments that have occurred since the publication of the original edition. New to the Second Edition A new chapter on the multivariate normal distribution, its general properties, and the concept of maximum-likelihood estimation More complete coverage of descriptive factor analysis and doublet factor analysis A rewritten chapter on analytic oblique rotation that focuses on the gradient projection algorithm and its applications Discussions on the developments of factor score indeterminacy A revised chapter on confirmatory factor analysis that addresses philosophy of science issues, model specification and identification, parameter estimation, and algorithm derivation Presenting the mathematics only as needed to understand the derivation of an equation or procedure, this textbook prepares students for later courses on structural equation modeling. It enables them to choose the proper factor analytic procedure, make modifications to the procedure, and produce new results.

The Enzyme Reference

A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods

Author: Daniel L. Purich,R. Donald Allison

Publisher: Elsevier

ISBN: 0080550819

Category: Science

Page: 929

View: 2326

The aim of this work is to provide a fuller spectrum of information in a single source on enzyme-catalyzed reactions than is currently available in any published reference work or as part of any Internet database. The Enzyme Reference: A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods includes 20,000 review articles and seminal research papers. Additionally, it provides a novel treatment of so-called ATPase and GTPase reactions to account for the noncovalent substratelike and productlike states of molecular motors, elongation factors, transporters, DNA helicases, G-reulatory proteins, and other energases. Includes a compendium of over 6,000 enzyme reactions (including enzyme commission numbers, alternative names, substrates, products, alternative substrates, and properties) Covers over 900 chemical structures of key metabolites and cofactors Index directs readers to the exact pages for over 9,500 enzyme names

Foundations of Neuroscience

Author: Marcus Jacobson

Publisher: Springer Science & Business Media

ISBN: 9780306445408

Category: Medical

Page: 387

View: 5874

The author makes a unique contribution to the field by discussing the history and philosophy of the neurosciences, and then developing critical approaches which integrate techniques, theory, and ethics. Taken as a whole, Jacobson's work will provide a coherent and humane framework for future research programs. The paperback edition of this highly successful text, first published in 1993, is now available! The author brings the ethics of neuroscience into a closer relationship with empirical research. Covering the field's history, philosophy, theories, and techniques, this volume provides the necessary moral and ethical framework to evaluate neuroscience research.

The Molecular Foundations of Psychiatry

Author: Steven E. Hyman,Eric Jonathan Nestler

Publisher: American Psychiatric Pub

ISBN: 9780880483537

Category: Medical

Page: 239

View: 2444

This text offers a comprehensive introduction to molecular biology, genetics, and neurobiology relevant to psychiatry. Generously illustrated chapters are organized to be read at both an introductory and a more advanced level. Both beginners and advanced professionals will benefit from this text's discussion of how psychotropic drugs work and how gene-environment interactions may contribute to the pathogenesis of psychiatric disorders. The authors demonstrate how molecular investigations in psychiatry will revolutionize the field by leading to improved diagnostic testing, to new and more effective treatments, and ultimately to the development of preventive measures for mental illness.