This book introduces the fundamental chemistry of the molecules that are essential to all cells, covering amino acids and sugar phosphate derivatives, and the macromolecules derived from them. In such a short text it is not possible to provide a comprehensive account of such molecules; instead it covers important concepts concerning their intrinsic chemistry. The aim is to provide the fundamental ideas relating to the chemistry of life that can then be applied to more advanced aspects of chemical biology.
Author: Christopher M. Dobson,Juliet A. Gerrard,Andrew J. Pratt
Publisher: Oxford University Press, USA
Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features * Explains how to use coordinate databases and atomic coordinates of biological macromolecules * Teaches the skills of stereoviewing * Contains computer-generated stereographics * Describes the principles of symmetry and handedness in proteins and DNA * Introduces metal and lipid binding proteins and DNA-protein interactions * Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions
Author: Leonard J. Banaszak
Biological chemistry has changed since the completion of the human genome project. There is a renewed interest and market for individuals trained in biophysical chemistry and molecular biophysics. The Physical Basis of Biochemistry, Second Edition, emphasizes the interdisciplinary nature of biophysical chemistry by incorporating the quantitative perspective of the physical sciences without sacrificing the complexity and diversity of the biological systems, applies physical and chemical principles to the understanding of the biology of cells and explores the explosive developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies that have occurred in the past seven years. The book features problem sets and examples, clear illustrations, and extensive appendixes that provide additional information on related topics in mathematics, physics and chemistry.
The Foundations of Molecular Biophysics
Author: Peter R. Bergethon
Publisher: Springer Science & Business Media
Take your first steps in combinatorial synthesis or synthesize bioactive molecules such as antibiotics. Search for mutations in DNA using chemical probes or perform a proteome analysis in yeast. The present selection of 12 inspiring experiments is tailored for maximum learning effect at minimal expense of time and equipment. Almost all currently used laboratory techniques in synthesis and analysis of bioactive compounds are represented at least once. Abundant practical hints are complemented by a thorough treatment of the underlying theory and mechanisms.
Author: Herbert Waldmann,Petra Janning
A new scientific discipline, acknowledged 65 years after its discovery, was the focus of the first Conference on Neuroimmune Biology in Canada. The papers presented at the conference, and in this volume, are dedicated to Dr. Hans Selye who is recognized as discovering the existence of a hypothalamic-pituitary-adrenal-thymus axis. This axis plays an important role in the adaptation of higher animals and man to various physical, chemical, biological and emotional challenges. The conference and participants also honored Dr. Andor Szentivanyi whose opening paper, "Studies on the hypothalamic regulation of histamine synthesis", is contained in the introduction to this book. Dr. Szentivanyi has dedicated his long research career to the clarification of the role of the central nervous system in immune and inflammatory reactions, and his experimental results are presented here. With an ultimate goal to achieve a more thorough understanding of higher organisms in their entire complexity, this book, the first in the series http://serval.elsevier.com/locate/series/nibNeuroImmune Biology presents a coordinated and integrated view of the growing body of knowledge rapidly accumulating in this area.
Author: I. Berczi,R.M. Gorczynski
Author: Sidney William Benson
Publisher: Krieger Pub Co
"For courses in General, Organic, and Biological Chemistry (2 - Semester)" A Clear, Flexible Approach to Chemistry for the Modern Classroom Active learning, an increased focus on clinical examples, updates based on current teaching and research findings, and digital innovations designed to engage and personalize readers experience make "Fundamentals of General, Organic, and Biological Chemistry" simply the best choice for readers with a future in allied health. With the Eighth Edition, the authors make learning chemistry a more active experience through features designed to get readers doing chemistry. Every chapter features "Hands on Chemistry" sections that deepen readers understanding of chemistry by having them perform elementary experiments with everyday household items. Group Problemsat the end of every chapter are designed for in-class use and motivate readers to carefully think about higher-level problems, such as how concepts fit together and how to apply these concepts in a clinical application. All of the chapter openers, including many of the Chemistry in Action boxes and end-of-chapter problems, have been rewritten for a stronger clinical focus that provides more relevance to allied health majors. All content has been updated for the modern classroom with special attention to the biochemistry chapters, making the Eighth Edition of "Fundamentals of General, Organic and Biological Chemistry " the best choice for future allied health readers. This edition is fully integrated with MasteringChemistry to provide an interactive and engaging experience. Media resources include narrated Video Tutor Solutions for every book chapter that present how to work the most challenging problems and feature additional feedback and instruction from contributor Sara Madsen. NEW in MasteringChemistry is the Chemistry Primer, a diagnostic and remediation tool that provides pre-built assignments designed to get readers up to speed on Chemistry and Math skills at the beginning of the course so they come to class prepared to delve more deeply into topics. Also Available with MasteringChemistry MasteringChemistry is the leading online homework, tutorial, and assessment system, designed to improve results by engaging students before, during, and after class with powerful content. Instructors ensure students arrive ready to learn by assigning educationally effective content before class, and they encourage critical thinking and retention with in-class resources such as Learning Catalytics . Students can further master concepts after class through traditional and adaptive homework assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess student understanding and misconceptions. Mastering brings learning full circle by continuously adapting to each student and making learning more personal than ever before, during, and after class. Note: You are purchasing a standalone product; MasteringChemistry does not come packaged with this content. Students, if interested in purchasing this title with MasteringChemistry, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and MasteringChemistry, search for 0134033094 / 9780134033099 " Fundamentals of General, Organic, and Biological Chemistry Plus MasteringChemistry with eText -- Access Card Package " Package consists of: 0134143337 / 9780134143330 "MasteringChemistry with Pearson eText -- ValuePack Access Card -- for Fundamentals of General, Organic, and Biological Chemistry" 0134015185 / 9780134015187 "Fundamentals of General, Organic, and Biological Chemistry" "
Author: John E. McMurry,David S. Ballantine, Jr.,Virginia E. Peterson,Carl A. Hoeger
Publisher: Prentice Hall
Author: Peter Raven
Publisher: McGraw-Hill Science/Engineering/Math
“This excellent work fills the need for an upper-level graduate course resource that examines the latest biochemical, biophysical, and molecular biological methods for analyzing the structures and physical properties of biomolecules… This reviewer showed [the book] to several of his senior graduate students, and they unanimously gave the book rave reviews. Summing Up: Highly recommended…” CHOICE Chemical biology is a rapidly developing branch of chemistry, which sets out to understand the way biology works at the molecular level. Fundamental to chemical biology is a detailed understanding of the syntheses, structures and behaviours of biological macromolecules and macromolecular lipid assemblies that together represent the primary constituents of all cells and all organisms. The subject area of chemical biology bridges many different disciplines and is fast becoming an integral part of academic and commercial research. This textbook is designed specifically as a key teaching resource for chemical biology that is intended to build on foundations lain down by introductory physical and organic chemistry courses. This book is an invaluable text for advanced undergraduates taking biological, bioorganic, organic and structural chemistry courses. It is also of interest to biochemists and molecular biologists, as well as professionals within the medical and pharmaceutical industry. Key Features: A comprehensive introduction to this dynamic area of chemistry, which will equip chemists for the task of understanding and studying the underlying principles behind the functioning of biological macro molecules, macromolecular lipid assemblies and cells. Covers many basic concepts and ideas associated with the study of the interface between chemistry and biology. Includes pedagogical features such as: key examples, glossary of equations, further reading and links to websites. Clearly written and richly illustrated in full colour.
Structure and Dynamics of Biological Macromolecules
Author: Andrew D. Miller,Julian Tanner
Publisher: John Wiley & Sons
Expert Preparation for the Revised MCAT--in Print, Online, and Mobile Totally geared to the brand-new test introduced in 2015, this book offers concise summaries of all important concepts, textbook-quality scientific diagrams, and abundant practice questions. The unique Cross-Platform format adds outstanding value: students can study the whole program in print, online, or on a mobile device. About the Book This volume of McGraw-Hill Education's four-book MCAT test-prep series covers the life sciences topics that MCAT candidates need to master. Chapters are organized around the “Foundational Concepts” specified in the MCAT syllabus. Each unit ends with a Minitest in MCAT format to give students ample practice with MCAT-style questions. Closely follows the MCAT syllabus created for the all-new 2015 test EXPANDED! Practice with MCAT-style questions on every topic Textbook-quality illustrations to enhance understanding Focuses tightly on topics tested on the MCAT About the Cross-Platform format: The Cross-Platform format provides a fully-comprehensive print, online, and mobile program: Entire instructional content available in print and digital form Personalized study plan and daily goals Powerful analytics to assess test readiness Flashcards, games, and social media for additional support About the Authors George Hademenos, Ph.D., is Assistant Professor at the University of Dallas, where he teaches General Physics and Quantum Physics. He has also taught at the University of Massachusetts and at UCLA. Candice McCloskey Campbell, Ph.D., is Assistant Professor of Chemistry at Georgia Perimeter College (Dunwoody, GA). Shaun Murphree, Ph.D., is Assistant Professor of Chemistry at Allegheny College (Meadville, PA). Jennifer M. Warner, Ph.D., teaches biology at the University of North Carolina, Charlotte. Amy B. Wachholz, Ph.D., is Director of Health Psychology at UMass Medical School (Worcester, MA). Kathy A. Zahler, MS, is a widely published test-prep author.
Author: George J. Hademenos
Publisher: McGraw Hill Professional
Category: Study Aids
This Primer covers the foundations of spectroscopy at a level suitable for first year chemistry undergraduates. Mass spectrometry, and X-ray diffraction, along with traditional spectroscopic techniques: i.r., n.m.r. and u.v. -visible spectroscopy are covered. The essential physical principles of each method are introduced, and many examples of spectral analysis provided. Problems, and further reading are also included. This Primer is designed to reflect the recent advances in the use of spectroscopic and diffraction methods, not only for obtaining an analysis of elements and groups present in a molecule but also for establishing the arrangement of the constituent atoms. These developments have had a profound effect by increasing scientific knowledge in the fields of chemistry and molecular biology, reflected in the elucidation of the structure and function of a wide range of compounds including drugs, proteins and enzymes, and nucleic acids.
Author: Simon B. Duckett,Bruce C. Gilbert
Publisher: Oxford University Press
Category: Language Arts & Disciplines
This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.
With Biochemical and Biophysical Foundations
Author: Mary Luckey
Publisher: Cambridge University Press
Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies. * Answers the question of what distinguishes the living from the non-living * An in-depth look to a vigorous and expanding discipline, from molecule to system * Explores the region between individual components and the system
Author: Fred Boogerd,Frank J. Bruggeman,Jan-Hendrik S. Hofmeyr,H.V. Westerhoff
It is widely recognised that mainstream economics has failed to translate micro consistently into macro economics and to provide endogenous explanations for the continual changes in the economic system. Since the early 1980s, a growing number of economists have been trying to provide answers to these two key questions by applying an evolutionary approach. This new departure has yielded a rich literature with enormous variety, but the unifying principles connecting the various ideas and views presented are, as yet, not apparent. This 2005 volume brings together fifteen original articles from scholars - each of whom has made a significant contribution to the field - in their common effort to reconstruct economics as an evolutionary science. Using meso economics as an analytical entity to bridge micro and macro economics as well as static and dynamic realms, a unified economic theory emerges.
Author: Kurt Dopfer
Publisher: Cambridge University Press
Category: Business & Economics
Retaining the concise, to-the-point presentation that has already helped thousands of readers move beyond memorization to a true understanding of the beauty and logic of organic chemistry, this Seventh Edition of John McMurry's FUNDAMENTALS OF ORGANIC CHEMISTRY brings in new, focused content that demonstrates how organic chemistry applies to everyday life. In addition, enhanced and redrawn chemical structures and artwork help readers visualize important chemical concepts, while a greater emphasis on biologically-related chemistry (including new problems) help readers grasp the enormous importance of organic chemistry in understanding the reactions that occur in living organisms. Lastly, for this edition, John McMurry reevaluated and revised his writing at the sentence level to ensure that the book's explanations, applications, and examples maximize reader understanding and are more clear, relevant, and motivating than ever before.
Author: John McMurry
Publisher: Nelson Education
Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene
Author: Natalie Kuldell PhD.,Rachel Bernstein,Karen Ingram,Kathryn M Hart
Publisher: "O'Reilly Media, Inc."