Essential Statistics for the Pharmaceutical Sciences

Author: Philip Rowe

Publisher: John Wiley & Sons

ISBN: 1118913418

Category: Medical

Page: 432

View: 8808

Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in research in pharmacology, pharmacy or other areas of pharmaceutical science; everybody from undergraduate project students to experienced researchers should find the material they need. This book will guide all those who are not specialist statisticians in using sound statistical principles throughout the whole journey of a research project - designing the work, selecting appropriate statistical methodology and correctly interpreting the results. It deliberately avoids detailed calculation methodology. Its key features are friendliness and clarity. All methods are illustrated with realistic examples from within pharmaceutical science. This edition now includes expanded coverage of some of the topics included in the first edition and adds some new topics relevant to pharmaceutical research. a clear, accessible introduction to the key statistical techniques used within the pharmaceutical sciences all examples set in relevant pharmaceutical contexts. key points emphasised in summary boxes and warnings of potential abuses in ‘pirate boxes’. supplementary material - full data sets and detailed instructions for carrying out analyses using packages such as SPSS or Minitab – provided at www.ljmu.ac.uk/pbs/rowestats/ An invaluable introduction to statistics for any science student and an essential text for all those involved in pharmaceutical research at whatever level.

A Practical Approach to Using Statistics in Health Research

From Planning to Reporting

Author: Adam Mackridge,Philip Rowe

Publisher: John Wiley & Sons

ISBN: 1119383595

Category: Medical

Page: 240

View: 1499

A hands-on guide to using statistics in health research, from planning, through analysis, and on to reporting A Practical Approach to Using Statistics in Health Research offers an easy to use, step-by-step guide for using statistics in health research. The authors use their experience of statistics and health research to explain how statistics fit in to all stages of the research process. They explain how to determine necessary sample sizes, interpret whether there are statistically significant difference in outcomes between groups, and use measured effect sizes to decide whether any changes are large enough to be relevant to professional practice. The text walks you through how to identify the main outcome measure for your study and the factor which you think may influence that outcome and then determine what type of data will be used to record both of these. It then describes how this information is used to select the most appropriate methods to report and analyze your data. A step-by-step guide on how to use a range of common statistical procedures are then presented in separate chapters. To help you make sure that you are using statistics robustly, the authors also explore topics such as multiple testing and how to check whether measured data follows a normal distribution. Videos showing how to use computer packages to carry out all the various methods mentioned in the book are available on our companion web site. This book: • Covers statistical aspects of all the stages of health research from planning to final reporting • Explains how to report statistical planning, how analyses were performed, and the results and conclusion • Puts the spotlight on consideration of clinical significance and not just statistical significance • Explains the importance of reporting 95% confidence intervals for effect size • Includes a systematic guide for selection of statistical tests and uses example data sets and videos to help you understand exactly how to use statistics Written as an introductory guide to statistics for healthcare professionals, students and lecturers in the fields of pharmacy, nursing, medicine, dentistry, physiotherapy, and occupational therapy, A Practical Approach to Using Statistics in Health Research:From Planning to Reporting is a handy reference that focuses on the application of statistical methods within the health research context.

Essential Statistical Methods for Medical Statistics

Author: J. Philip Miller

Publisher: Elsevier

ISBN: 9780444537386

Category: Mathematics

Page: 368

View: 7144

Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. · Contributors are internationally renowned experts in their respective areas · Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research · Methods for assessing Biomarkers, analysis of competing risks · Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs · Structural equations modelling and longitudinal data analysis

Statistical Methods for Pharmaceutical Research Planning

Author: S. W. Bergman

Publisher: CRC Press

ISBN: 9780824771461

Category: Mathematics

Page: 272

View: 7572

The first comprehensive survey of the procedures devised by statisticians and operational researchers to expedite the early stages of pharmaceutical and agri-chemical research, this useful text describes and evaluates all major methodologies, in some cases extending them and offering new ones for the first time. Statistical Methods for Pharmaceutical Research Planning provides ample, non-technical summaries of each method ... gathers information from widely scattered sources ... discusses general statistical methodology not designed specifically for pharmaceutical research ... investigates statistically based procedures, developed by such major figures as Free, Hansch, and Wilson, for finding active compounds ... examines the design of single screens and sequences of screens for testing candidate compounds ... looks at methods for research project selection, devised mainly by management scientists without specific reference to pharmaceutical research ... and contains hundreds of references to sources for further research, plus numerous tables, equations, and line drawings. Statistical Methods for Pharmaceutical Research Planning is essential reading for all those directly or indirectly concerned with planning pharmaceutical and agri-chemical research: statisticians, particularly biostatisticians, pharmacologists, chemists, biologists, research managers, management scientists, and operational researchers. It is also a valuable supplement for graduate-level courses on statistics and operational research. Book jacket.

The Essentials of Biostatistics for Physicians, Nurses, and Clinicians

Author: Michael R. Chernick

Publisher: John Wiley & Sons

ISBN: 1118071948

Category: Medical

Page: 228

View: 3799

A fundamental and straightforward guide to using and understanding statistical concepts in medical research Designed specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today's biomedical research and provides insight on their appropriate application. Rather than provide detailed mathematics for each of these methods, the book emphasizes what healthcare practitioners need to know to interpret and incorporate the latest biomedical research into their practices. The author draws from his own experience developing and teaching biostatistics courses for physicians and nurses, offering a presentation that is non-technical and accessible. The book begins with a basic introduction to the relationship between biostatistics and medical research, asking the question "why study statistics?," while also exploring the significance of statisitcal methods in medical literature and clinical trials research. Subsequent chapters explore key topics, including: Correlation, regression, and logistic regression Diagnostics Estimating means and proportions Normal distribution and the central limit theorem Sampling from populations Contingency tables Meta-analysis Nonparametric methods Survival analysis Throughout the book, statistical methods that are often utilized in biomedical research are outlined, including repeated measures analysis of variance, hazard ratios, contingency tables, log rank tests, bioequivalence, cross-over designs, selection bias, and group sequential methods. Exercise sets at the end of each chapter allow readers to test their comprehension of the presented concepts and techniques. The Essentials of Biostatistics for Physicians, Nurses, and Clinicians is an excellent reference for doctors, nurses, and other practicing clinicians in the fields of medicine, public health, pharmacy, and the life sciences who need to understand and apply statistical methods in their everyday work. It also serves as a suitable supplement for courses on biostatistics at the upper-undergraduate and graduate levels.

Pharmaceutical Statistics

Author: David S. Jones

Publisher: Pharmaceutical Press

ISBN: 9780853694250

Category: Medical

Page: 586

View: 9419

Pharmaceutical Statistics is a new publication on basic statistics, specifically written for pharmacy students. It contains chapters on basic concepts such as types of data, graphical representation of data, distribution and standard deviation. More advanced, frequently used, statistical techniques such as ANOVA and the chi-squared test are also discussed using pharmaceutical examples. Pharmaceutical Statistics is essential reading for all pharmacy students and will also be of interest to those working in the pharmaceutical industry.

Drogen

Die Geschichte eines langen Krieges

Author: Johann Hari

Publisher: S. Fischer Verlag

ISBN: 3104035687

Category: Fiction

Page: 448

View: 6049

»Hari vereint präzise Recherche mit einer zutiefst menschlichen Erzählung. Dieses Buch wird eine dringend notwendige Debatte auslösen.« Glenn Greenwald Der Krieg gegen die Drogen gilt inzwischen als gescheitert, der Handel mit Drogen ist ein blühendes Geschäft, alle Maßnahmen gegen den Konsum sind weitgehend erfolglos. Woran liegt das? Der britische Journalist Johann Hari begibt sich auf eine einzigartige Reise – von Brooklyn über Mexiko bis nach Deutschland – und erzählt die Geschichten derjenigen, deren Leben vom immerwährenden Kampf gegen Drogen geprägt ist: von Dealern, Süchtigen, Kartellmitgliedern, den Verlierern und Profiteuren. Mit seiner grandiosen literarischen Reportage schreibt Hari sowohl eine Geschichte des Krieges gegen Drogen als auch ein mitreißendes und streitbares Plädoyer zum Umdenken. »Hervorragender Journalismus, packend erzählt.« Naomi Klein »Phantastisch!« Noam Chomsky

Methods and Applications of Statistics in the Life and Health Sciences

Author: N. Balakrishnan

Publisher: John Wiley & Sons

ISBN: 0470405090

Category: Mathematics

Page: 986

View: 3948

"Data collection holds an essential part in dictating the future of health sciences and public health, as the compilation of statistics allows researchers and medical practitioners to monitor trends in health status, identify health problems, and evaluate the impact of health policies and programs. Methods and Applications of Statistics in the Life and Health Sciences serves as a single, one-of-a-kind resource on the wide range of statistical methods, techniques, and applications that are applied in modern life and health sciences in research. Specially designed to present encyclopedic content in an accessible and self-contained format, this book outlines thorough coverage of the underlying theory and standard applications to research in related disciplines such as biology, epidemiology, clinical trials, and public health. Uniquely combining established literature with cutting-edge research, this book contains classical works and more than twenty-five new articles and completely revised contributions from the acclaimed Encyclopedia of Statistical Sciences, Second Edition. The result is a compilation of more than eighty articles that explores classic methodology and new topics."--Publisher's description.

10 Essentials for High Performance Quality in the 21st Century

Author: Diomidis H. Stamatis

Publisher: CRC Press

ISBN: 1439876010

Category: Business & Economics

Page: 360

View: 9569

As a society, we tend to reward problem solvers, rather than those who prevent problems at their source. In other words, we focus on after-the-fact occurrences (appraisal activities) instead of trying to eliminate these occurrences (preventing activities). Discussing and evaluating the core requirements of quality efficiency and improvement, 10 Essentials for High Performance Quality in the 21st Century proposes an approach to help shift the paradigm of quality from appraisal mode to preventing mode. Identifying 10 steps readers can follow to optimize the quality of products and improve customer satisfaction, the book explains the rationale behind each of the steps in separate chapters. It addresses specific quality issues in six different sectors of the economy and provides statistics, tables, and figures from various organizations that support the need for a paradigm shift. Outlining a systematic process to guide your organization along the path toward improvement, the book covers risk and quality, multicultural management, empowerment, error analysis, team building, advanced quality planning, and quality operating systems. The accompanying CD provides tips and tools to help you implement all the necessary improvement initiatives under the umbrella of quality.

Multivariate Analysis for the Biobehavioral and Social Sciences

A Graphical Approach

Author: Bruce L. Brown,Suzanne B. Hendrix,Dawson W. Hedges,Timothy B. Smith

Publisher: John Wiley & Sons

ISBN: 1118131614

Category: Mathematics

Page: 496

View: 1948

An insightful guide to understanding and visualizing multivariatestatistics using SAS®, STATA®, and SPSS® Multivariate Analysis for the Biobehavioral and Social Sciences:A Graphical Approach outlines the essential multivariate methodsfor understanding data in the social and biobehavioral sciences.Using real-world data and the latest software applications, thebook addresses the topic in a comprehensible and hands-on manner,making complex mathematical concepts accessible to readers. The authors promote the importance of clear, well-designedgraphics in the scientific process, with visual representationsaccompanying the presented classical multivariate statisticalmethods . The book begins with a preparatory review of univariatestatistical methods recast in matrix notation, followed by anaccessible introduction to matrix algebra. Subsequent chaptersexplore fundamental multivariate methods and related key concepts,including: Factor analysis and related methods Multivariate graphics Canonical correlation Hotelling's T-squared Multivariate analysis of variance (MANOVA) Multiple regression and the general linear model (GLM) Each topic is introduced with a research-publication case studythat demonstrates its real-world value. Next, the question "how doyou do that?" is addressed with a complete, yet simplified,demonstration of the mathematics and concepts of the method.Finally, the authors show how the analysis of the data is performedusing Stata®, SAS®, and SPSS®. The discussedapproaches are also applicable to a wide variety of modernextensions of multivariate methods as well as modern univariateregression methods. Chapters conclude with conceptual questionsabout the meaning of each method; computational questions that testthe reader's ability to carry out the procedures on simpledatasets; and data analysis questions for the use of the discussedsoftware packages. Multivariate Analysis for the Biobehavioral and Social Sciencesis an excellent book for behavioral, health, and social sciencecourses on multivariate statistics at the graduate level. The bookalso serves as a valuable reference for professionals andresearchers in the social, behavioral, and health sciences whowould like to learn more about multivariate analysis and itsrelevant applications.

Essentials of Law for Health Professionals

Author: Kim Forrester,Debra Griffiths

Publisher: Elsevier Health Sciences

ISBN: 0729579158

Category: Medical

Page: 400

View: 5391

Essentials of Law for Health Professionals 3e has been thoroughly revised and updated throughout to reflect the most recent changes in legislation relevant to the provision of health care services in Australia. Employment status of health professionals and issues of work cover, health and safety obligations, anti-discrimination issues are clearly outlined and discussed in the new edition. Legal issues surrounding genetics, fertility and surrogacy are reviewed in conjunction with the current position on abortion and wrongful deaths. The breadth of material is presented in a manner that is more in keeping with a student resource text rather than a law book. It emphasises major points and includes summaries on how the law relates to practice rather than merely stating the law. The new third edition continues to present contemporary issues relevant for Health Science students from the clinical setting through to management and employment, as they apply to each state. Streamlined new edition includes updates to key chapters such as: Chapter 5 Negligence, which has been completely rewritten to discuss negligence by jurisdiction Chapter 8 Manipulation of Life now deals with topical and controversial issues such as abortion, wrongful death, tissue transplants, genetics and infertility Chapter 10: Contractual and Industrial Elements of Professional Practice has been updated to include the most recent changes to Industrial Relations Law, information that is essential for any Health Professional entering into employment. Chapter 11: Statues Controlling Health Service Delivery has been revised with respect to drugs and continues to provide the significant legislation most likely to impact on the daily practice of the health professional namely poisons, mental health legislation, child and elder abuse, and the notification of births and deaths. New Chapter 12: Registration and Regulation of Health Professionals highlights the contemporary issues faced by health professionals with the implementation of National Registration. Addition of legislation regulating research and a discussion of the legislative and common law controls on conducting research within Australian healthcare systems – National Health and Medical Research Council Act Update all appendices and include the Decision Making Framework for Nurses plus Glossary Takes a multidisciplinary approach to the subject of health care law and includes case-studies and activities. Discussion on the implications of evidence-based practice on the standard notionally attributed to the duty of care.

Statistik-Workshop für Programmierer

Author: Allen B. Downey

Publisher: O'Reilly Germany

ISBN: 3868993436

Category: Computers

Page: 160

View: 416

Wenn Sie programmieren können, beherrschen Sie bereits Techniken, um aus Daten Wissen zu extrahieren. Diese kompakte Einführung in die Statistik zeigt Ihnen, wie Sie rechnergestützt, anstatt auf mathematischem Weg Datenanalysen mit Python durchführen können. Praktischer Programmier-Workshop statt grauer Theorie: Das Buch führt Sie anhand eines durchgängigen Fallbeispiels durch eine vollständige Datenanalyse -- von der Datensammlung über die Berechnung statistischer Kennwerte und Identifikation von Mustern bis hin zum Testen statistischer Hypothesen. Gleichzeitig werden Sie mit statistischen Verteilungen, den Regeln der Wahrscheinlichkeitsrechnung, Visualisierungsmöglichkeiten und vielen anderen Arbeitstechniken und Konzepten vertraut gemacht. Statistik-Konzepte zum Ausprobieren: Entwickeln Sie über das Schreiben und Testen von Code ein Verständnis für die Grundlagen von Wahrscheinlichkeitsrechnung und Statistik: Überprüfen Sie das Verhalten statistischer Merkmale durch Zufallsexperimente, zum Beispiel indem Sie Stichproben aus unterschiedlichen Verteilungen ziehen. Nutzen Sie Simulationen, um Konzepte zu verstehen, die auf mathematischem Weg nur schwer zugänglich sind. Lernen Sie etwas über Themen, die in Einführungen üblicherweise nicht vermittelt werden, beispielsweise über die Bayessche Schätzung. Nutzen Sie Python zur Bereinigung und Aufbereitung von Rohdaten aus nahezu beliebigen Quellen. Beantworten Sie mit den Mitteln der Inferenzstatistik Fragestellungen zu realen Daten.

Clinical Trial Methodology

Author: Karl E. Peace,Ding-Geng (Din) Chen

Publisher: CRC Press

ISBN: 9781584889182

Category: Mathematics

Page: 420

View: 7136

Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial. Drawing from the authors’ courses on the subject as well as the first author’s more than 30 years working in the pharmaceutical industry, Clinical Trial Methodology emphasizes the importance of statistical thinking in clinical research and presents the methodology as a key component of clinical research. From ethical issues and sample size considerations to adaptive design procedures and statistical analysis, the book first covers the methodology that spans every clinical trial regardless of the area of application. Crucial to the generic drug industry, bioequivalence clinical trials are then discussed. The authors describe a parallel bioequivalence clinical trial of six formulations incorporating group sequential procedures that permit sample size re-estimation. The final chapters incorporate real-world case studies of clinical trials from the authors’ own experiences. These examples include a landmark Phase III clinical trial involving the treatment of duodenal ulcers and Phase III clinical trials that contributed to the first drug approved for the treatment of Alzheimer’s disease. Aided by the U.S. FDA, the U.S. National Institutes of Health, the pharmaceutical industry, and academia, the area of clinical trial methodology has evolved over the last six decades into a scientific discipline. This guide explores the processes essential for developing and conducting a quality clinical trial protocol and providing quality data collection, biostatistical analyses, and a clinical study report, all while maintaining the highest standards of ethics and excellence.

Voigt's Pharmaceutical Technology

Author: Alfred Fahr

Publisher: John Wiley & Sons

ISBN: 1118972627

Category: Science

Page: 888

View: 6778

A textbook which is both comprehensive and comprehensible and that offers easy but scientifically sound reading to both students and professionals Now in its 12th edition in its native German, Voigt's Pharmaceutical Technology is an interdisciplinary textbook covering the fundamental principles of pharmaceutical technology. Available for the first time in English, this edition is produced in full colour throughout, with a concise, clear structure developed after consultation with students, instructors and researchers. This book: Features clear chapter layouts and easily digestible content Presents novel trends, devices and processes Discusses classical and modern manufacturing processes Covers all formulation principles including tablets, ointments, capsules, nanosystems and biopharmaceutics Takes account of legal requirements for both qualitative and quantitative composition Addresses quality assurance considerations Uniquely relates contrasting international pharmacopeia from EU, US and Japan to formulation principles Includes examples and text boxes for quicker data assimilation Written for both students studying pharmacy and industry professionals in the field as well as toxicologists, biochemists, medical lab technicians, Voigt’s Pharmaceutical Technology is the essential resource for understanding the various aspects of pharmaceutical technology.

Pharmaceutical Sciences

A Treatise on the Theory and Practice of Pharmaceutical Sciences, with Essential Information about Pharmaceutical and Medicinal Agents; Also a Guide to the Profession Responsibilities and Services of the Pharmacist as a Member of the Health Team. A Textbook and Reference Work for Pharmacists, Physicians, and Other Medical Scientists

Author: Joseph Price Remington,John E. Hoover

Publisher: N.A

ISBN: N.A

Category:

Page: 1964

View: 3034


Pharmacology for the Primary Care Provider - E-Book

Author: Marilyn Winterton Edmunds,Maren Stewart Mayhew

Publisher: Elsevier Health Sciences

ISBN: 0323087914

Category: Medical

Page: 880

View: 3382

Written by and for nurse practitioners, and also suitable for physician’s assistants, Pharmacology for the Primary Care Provider, 4th Edition focuses on what you need to know to safely and effectively prescribe drugs for primary care. An emphasis on patient teaching helps you gain patient adherence to prescribed drug regimens, and guidelines for health promotion help in maintaining and improving your patients’ health. Now in full color, this edition expands the book's emphasis on the QSEN priorities of safety and evidence-based practice, and adds coverage of new drugs, new drug classes, and new therapeutic drug uses. Written by leading nurse practitioner authorities Marilyn Winterton Edmunds and Maren Stewart Mayhew, Pharmacology for the Primary Care Provider teaches principles of pharmacotherapeutics using today’s most commonly used drugs. A Key Drugs focus highlights the most commonly used and most representative drugs of each major drug class — with particular emphasis on the top 100 most commonly prescribed drugs. Emphasis on patient teaching helps you communicate with patients and family caregivers to promote adherence to the drug regimen. Emphasis on health promotion describes how to help patients stay well and improve their health, including coverage of immunizations and biologicals, vitamins, weight management, and smoking cessation. Evidence-Based Decision-Making and Treatment Guidelines chapter (11) provides practical guidelines for using the best current research evidence to make decisions about the care of individual patients. Extensive coverage of drug therapy for special populations such as geriatric and pediatric patients includes considerations related to age, pregnancy, race, and other factors. UNIQUE! Coverage of prescriptive practice includes topics such as prescriptive authority, role implementation, and the role of nurses (NPs, CNMs, CRNAs, and CNSs) and physician assistants in writing prescriptions. NEW! Full-color design and illustrations highlight the most important content. DRUG UPDATES reflect the latest FDA-approved drugs, drug classes, and therapeutic uses. Expanded emphasis on the QSEN priorities of safety and evidence-based practice helps you eliminate drug prescribing errors with color-highlighted Safety Alerts! and NEW Clinical Practice Alerts! NEW section on male hormone replacement therapies adds coverage of men to that for women. Updated evidence-based prescribing information reflects the latest national clinical practice guidelines and evidence-based treatment guidelines, including the latest clinical treatment guidelines for diabetes. NEW! Complementary and Alternative Products tables highlight interactions with drugs, and are emphasized with a distinctive icon. Updated Drug Overview tables are enhanced with color as well as Top 100 icons that highlight the most commonly prescribed drugs.

Practical Pharmaceutics

An International Guideline for the Preparation, Care and Use of Medicinal Products

Author: Yvonne Bouwman-Boer,V'Iain Fenton-May,Paul Le Brun

Publisher: Springer

ISBN: 3319158147

Category: Medical

Page: 878

View: 3367

This book contains essential knowledge on the preparation, control, logistics, dispensing and use of medicines. It features chapters written by experienced pharmacists working in hospitals and academia throughout Europe, complete with practical examples as well as information on current EU-legislation. From prescription to production, from usage instructions to procurement and the impact of medicines on the environment, the book provides step-by-step coverage that will help a wide range of readers. It offers product knowledge for all pharmacists working directly with patients and it will enable them to make the appropriate medicine available, to store medicines properly, to adapt medicines if necessary and to dispense medicines with the appropriate information to inform patients and caregivers about product care and how to maintain their quality. This basic knowledge will also be of help to industrial pharmacists to remind and focus them on the application of the medicines manufactured. The basic and practical knowledge on the design, preparation and quality management of medicines can directly be applied by the pharmacists whose main duty is production in community and hospital pharmacies and industries. Undergraduate as well as graduate pharmacy students will find knowledge and backgrounds in a fully coherent way and fully supported with examples.

Statistics and Experimental Design for Toxicologists, Third Edition

Author: Shayne C. Gad

Publisher: CRC Press

ISBN: 9780849331381

Category: Mathematics

Page: 448

View: 5901

This book serves as a primary text for students of pharmacology, toxicology, and biology, and as a practical handbook to support the daily operations of the toxicology laboratory and researcher. This edition retains the structure of earlier editions, but has been extensively revised to provide both the student and the working toxicologist with the necessary tools for the rigorous and critical design of studies and analysis of experimental data. Assuming only basic mathematical skills as a starting point, Statistics and Experimental Design for Toxicologists provides a thorough and exhaustive introduction to the statistical methods available to and used in the discipline. A worked, practical example from the field is provided for each technique presented. Written from a toxicologist's perspective, this book provides both the methodological tools necessary to analyze experimental toxicology data and the insight to know when to use them.