Biomaterials Science

An Introduction to Materials in Medicine

Author: Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons

Publisher: Academic Press

ISBN: 008087780X

Category: Medical

Page: 1573

View: 6070

The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: "the only such text that currently covers this area comprehensively" - Materials Today Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank

Biomaterials Science

An Introduction to Materials in Medicine

Author: Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons

Publisher: Elsevier

ISBN: 008047036X

Category: Science

Page: 864

View: 3331

The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. Provides comprehensive coverage of principles and applications of all classes of biomaterials Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites Endorsed by the Society for Biomaterials

Biomaterials Science

An Introduction to Materials in Medicine

Author: Buddy D. Ratner

Publisher: Academic Press

ISBN: 0125824637

Category: Science

Page: 851

View: 8578

"... This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials." -- Publisher's description.

Introduction to Biomaterials

Basic Theory with Engineering Applications

Author: J. L. Ong,Mark R. Appleford,Gopinath Mani

Publisher: Cambridge University Press

ISBN: 0521116902

Category: Medical

Page: 419

View: 6861

A succinct introduction to the field of biomaterials engineering, packed with practical insights.

An Introduction to Tissue-Biomaterial Interactions

Author: Kay C. Dee,David A. Puleo,Rena Bizios

Publisher: John Wiley & Sons

ISBN: 0471461121

Category: Science

Page: 248

View: 2818

An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices.

An Introduction to Biomaterials, Second Edition

Author: Jeffrey O. Hollinger

Publisher: CRC Press

ISBN: 143981256X

Category: Medical

Page: 644

View: 9255

A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.

Biomaterials

An Introduction

Author: Joon Park,R. S. Lakes

Publisher: Springer Science & Business Media

ISBN: 0387378804

Category: Technology & Engineering

Page: 562

View: 4250

With sixty years of combined experience, the authors of this extensively revised book have learned to emphasize the fundamental materials science, structure-property relationships, and biological responses as a foundation for a wide array of biomaterials applications. This edition includes a new chapter on tissue engineering and regenerative medicine, approximately 1900 references to additional reading, extensive tutorial materials on new developments in spinal implants and fixation techniques and theory. It also offers systematic coverage of orthopedic implants, and expanded treatment of ceramic materials and implants.

Introduction to BioMEMS

Author: Albert Folch

Publisher: CRC Press

ISBN: 1466509384

Category: Medical

Page: 528

View: 9519

The entire scope of the BioMEMS field—at your fingertips Helping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based devices, and implantable systems. It focuses on high-impact, creative work encompassing all the scales of life—from biomolecules to cells, tissues, and organisms. Brilliant color presentation Avoiding the overwhelming details found in many engineering and physics texts, this groundbreaking book—in color throughout—includes only the most essential formulas as well as many noncalculation-based exercises. Important terms are highlighted in bold and defined in a glossary. The text contains more than 400 color figures, most of which are from the original researchers. Coverage of both historical perspectives and the latest developments Developed from the author’s long-running course, this classroom-tested text gives readers a vivid picture of how the field has grown by presenting historical perspectives and a timeline of seminal discoveries. It also describes numerous state-of-the-art biomedical applications that benefit from "going small," including devices that record the electrical activity of brain cells, measure the diffusion of molecules in microfluidic channels, and allow for high-throughput studies of gene expression.

An Introduction to Bioceramics

Second Edition

Author: Larry L Hench

Publisher: World Scientific Publishing Company

ISBN: 1908977175

Category: Medical

Page: 620

View: 800

This is the second edition of the classic book An Introduction to Bioceramics which provides a comprehensive overview of all types of ceramic and glass materials that are used in medicine and dentistry. The enormous growth of the field of bioceramics is due to the recognition by the medical and dental community of the importance of bioactive materials to stimulate repair and regeneration of tissues. This edition includes 21 new chapters that document the science and especially the clinical applications of the new generation of bioceramics in the field of tissue regeneration and repair. Important socioeconomic factors influencing the economics and availability of new medical treatments are covered with updates on regulatory procedures for new biomaterials, methods for technology transfer and ethical issues. The book contains 42 chapters that offer the only comprehensive treatment of the science, technology and clinical applications of all types of bioceramic materials used in medicine and dentistry. Each chapter is written by leaders in their specialized fields and is a thorough review of the subject matter, unlike many conference proceedings. All chapters have been edited to reflect the same writing style, making the book an easy read. The completeness of treatment of all types of bioceramics and their clinical applications makes the book unique in the field and invaluable to all readers.

Nanobiotechnology

Concepts, Applications and Perspectives

Author: Christof M. Niemeyer,Chad A. Mirkin

Publisher: John Wiley & Sons

ISBN: 3527605916

Category: Science

Page: 491

View: 8856

Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology. Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments. It is divided into four main sections: * Interphase Systems * Protein-based Nanostructures * DNA-based Nanostructures * Nanoanalytics Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.

Biomaterials

A Basic Introduction

Author: Qizhi Chen,George Thouas

Publisher: CRC Press

ISBN: 1482227703

Category: Medical

Page: 736

View: 4860

Explores Biomedical Science from a Unique Perspective Biomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author’s course lecture notes and many years of research, it presents students with the knowledge needed to select and design biomaterials used in medical devices. Placing special emphasis on metallic, ceramic, polymeric, and composite biomaterials, it explains the difference between materials science and materials engineering, introduces basic concepts and principles, and analyzes the critically important properties of biomaterials. Explains Complex Theories Using Aspects of Daily Life This text provides an appropriate balance between depth and broadness of coverage, and offers an understanding of the most important concepts and principles to students from a wide academic spectrum. It delivers the science of biomaterials in laymen terms, from a material standpoint, as well as a clinical applications point of view. It equips students majoring in materials science/engineering with knowledge on the fundamentals of how biomaterials behave at a biological level, and provides students majoring in medicine with information that is generally unavailable in traditional medical courses. The authors incorporate learning objectives at the beginning of each chapter, as well as chapter highlights, problems, and exercises at the end of each chapter. In addition, they present objectives, suggested activities, and reference material for further reading. Contains an overview of medical science vis-à-vis materials science, describes anatomy, histology, and cell biology Highlights health issues and diseases where biomaterials can easily find medical applications Presents knowledge of the relationship between the biomaterials and the living body Evaluates medical devices and looks into their respective regulations Biomaterials: A Basic Introduction contains an overview of basic biomaterials and concepts, and is written for upper-division students in the US/Canada, and second-level students in universities worldwide.

Biomedical Instrumentation Systems

Author: Shakti Chatterjee,Aubert Miller

Publisher: Cengage Learning

ISBN: 1133714498

Category: Technology & Engineering

Page: 704

View: 3208

Learn to maintain and repair the high tech hospital equipment with this practical, straightforward, and thorough new book. Biomedical Instrumentation Systems uses practical medical scenarios to illustrate effective equipment maintenance and repair procedures. Additional coverage includes basic electronics principles, as well as medical device and safety standards. Designed to provide readers with the most current industry information, the latest medical websites are referenced, and today's most popular software simulation packages like MATLAB and MultiSIM are utilized. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Characterization of Biomaterials

Chapter 1. Introduction to Biomaterials

Author: Susmita Bose,Amit Bandyopadhyay

Publisher: Elsevier Inc. Chapters

ISBN: 0128070951

Category: Science

Page: 450

View: 447

This brief introductory chapter provides a broad overview of materials, biomaterials and the need to understand different techniques to characterize biomaterials. From this chapter, the reader can gain a perspective on how the rest of the topics in different chapters are divided to fully comprehend this inherently multidisciplinary field. Application of appropriate characterization tools can not only save time to fully evaluate different biomaterials, it can also make commercial biomedical devices safer. In the long run, safer biomedical devices can only reduce the pain and suffering of mankind, a dream that resonates with every biomedical researcher.

Engineering Materials for Biomedical Applications

Author: Teoh Swee Hin

Publisher: World Scientific

ISBN: 9814481645

Category: Medical

Page: 352

View: 5909

The success of any implant or medical device depends very much on the biomaterial used. Synthetic materials (such as metals, polymers and composites) have made significant contributions to many established medical devices. The aim of this book is to provide a basic understanding on the engineering and processing aspects of biomaterials used in medical applications. Of paramount importance is the tripartite relationship between material properties, processing methods and design. As the target audiences cover a wide interdisciplinary field, each chapter is written with a detailed background so that audience of another discipline will be able to understand. For the more knowledgeable reader, a detailed list of references is included. Contents:Introduction to Biomaterials Engineering and Processing — An Overview (S H Teoh)Durability of Metallic Implant Materials (M Sumita & S H Teoh)Corrosion of Metallic Implants (D J Blackwood et al.)Surface Modification of Metallic Biomaterials (T Hanawa)Biorestorative Materials in Dentistry (A U J Yap)Bioceramics: An Introduction (B Ben-Nissan & G Pezzotti)Polymeric Hydrogels (J Li)Bioactive Ceramic-Polymer Composites for Tissue Replacement (M Wang)Composites in Biomedical Applications (Z M Huang & S Ramakrishna)New Methods and Materials in Prosthetics for Rehabilitation of Lower Limb Amputees (P V S Lee)Chitin-Based Biomaterials (E Khor) Readership: Undergraduates and postgraduates (in bioengineering, materials science and engineering, mechanical engineering, dental and orthopaedic departments), engineers, researchers, academics/lecturers and industrialists. Keywords:Biomaterials Engineering and Processing;Durability of Metallic Implants;Surface Modification;Dental Materials;Bioceramics;Polymeric Hydrogels;Composites;Prosthetics;ChitinKey Features:Contains detailed information on the latest biomaterials (such as polymers, metals, ceramics and composites ) used in medical devicesProvides a good understanding into the durability issues such as an in-depth treatment of corrosion and fretting fatigue of metallic implantsIt leads the reader to have a greater appreciation on the need for surface modification so as to enable the medical device to have the appropriate tissue response

New Functional Biomaterials for Medicine and Healthcare

Author: Elena P. Ivanova,Kateryna Bazaka,Roy J. Crawford

Publisher: Woodhead Publishing

ISBN: 1782422668

Category: Technology & Engineering

Page: 244

View: 8439

New Functional Biomaterials for Medicine and Healthcare provides a concise summary of the latest developments in key types of biomaterials. The book begins with an overview of the use of biomaterials in contemporary healthcare and the process of developing novel biomaterials; the key issues and challenges associated with the design of complex implantable systems are also highlighted. The book then reviews the main materials used in functional biomaterials, particularly their properties and applications. Individual chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics. Advances in processing technologies and our understanding of materials and their properties have made it possible for scientists and engineers to develop more sophisticated biomaterials with more targeted functionality. New Functional Biomaterials for Medicine and Healthcare provides an ideal one-volume summary of this important field that represents essential reading for scientists, engineers, and clinicians, and a useful reference text for undergraduate and postgraduate students. Provides a concise summary of the latest developments in key types of biomaterials Highlights key issues and challenges associated with the design of complex implantable systems Chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics

An Introduction to Biocomposites

Author: Seeram Ramakrishna,Zheng-Ming Huang,Ganesh V Kumar,Andrew W Batchelor,Joerg Mayer

Publisher: World Scientific

ISBN: 178326084X

Category: Technology & Engineering

Page: 236

View: 3815

Many years of cumulative research has been conducted on the usage of fiber-reinforced composites for biomedical application, but no one source exists where this topic is dealt with systematically. This book addresses polymer composites applied to bioengineering in a comprehensive manner. For potential applications to be successful, full advantage must be taken of the materials properties and the manufacturing techniques to meet the needs of biomedical application. This book focuses on fiber-based composites applied to bioengineering. It addresses three main areas. First, it presents a comprehensive survey of biocomposites from the existing literature in various medical applications, paying particular attention to hard-tissue-related implants. Second, mechanical designs and manufacturing aspects of various fibrous polymer matrix composites are described. The third area concerns examples of the design and development of several medical devices and implants using polymer composites. Chapter 1: Introduction (288 KB) Contents:BiocompatibilityConstituent, Fabrication, and CharacterizationMechanics of Composite MaterialsDesigning with Composite MaterialsBiomedical Applications of Polymer CompositesCase Studies Readership: Researchers and graduate students in bioengineering, polymers and mechanics. Keywords:Bioengineering;Composite Materials;Fiber;Polymer;Medical Devices;Design

Biomaterials

A Systems Approach to Engineering Concepts

Author: Brian J. Love

Publisher: Academic Press

ISBN: 0081010370

Category: Technology & Engineering

Page: 410

View: 1959

Biomaterials: A Systems Approach to Engineering Concepts provides readers with a systems approach to biomaterials and materials engineering. By focusing on the mechanical needs of implants, disease states, and current clinical needs, readers are encouraged to design materials and systems targeted at specific conditions, and to identify the impact of their proposed solutions. This inventive text is a useful resource for researchers, students, and course providers of biomaterials and biomedical engineering. Provides a fully comprehensive treatment relating to the construction and use of materials in medicine Presents perspectives of disease states to encourage the design of materials and systems targeted at specific conditions Defines current issues experienced by clinics to enable optimized engineering solutions

PEEK Biomaterials Handbook

Author: Steven M. Kurtz

Publisher: William Andrew

ISBN: 143774463X

Category: Technology & Engineering

Page: 298

View: 986

PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Full coverage of the properties and applications of PEEK, the leading polymer for spinal implants. PEEK is being used in a wider range of new applications in biomedical engineering, such as hip and knee replacements, and finger joints. These new application areas are explored in detail. Essential reference for plastics enginers, biomedical engineers and orthopedic professionals involved in the use of the PEEK polymer, and medical implants made from PEEK.

Biomaterials and Regenerative Medicine in Ophthalmology

Author: Traian Chirila,Damien Harkin

Publisher: Woodhead Publishing

ISBN: 0081001843

Category: Medical

Page: 502

View: 1126

Biomaterials and Regenerative Medicine in Ophthalmology, Second Edition, focuses on an aging population and the increasing instances of eye diseases. Biomaterials continue to be used for numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. This book provides readers with an updated and expanded look at the present status and future direction of biomaterials and regenerative medicine in this important field. Provides an integral and significant exploration of biomaterials and regenerative medicine, presenting crucial advances made in the fields of ophthalmology and optometry, such as the development of intraocular lenses and new applications for contact lens Presents a new and updated look at the future direction of biomaterials and regenerative medicine in this field Comprehensive coverage in a range of fields, including hydrogels, corneal tissue engineering, and stem cell therapies for the restoration of the ocular surface