Author: Tatsuaki Ishiguro

Publisher: Kodansha USA

ISBN: 1942993447

Category: Fiction

Page: 240

View: 8165

Told in the manner of scientific reports, this collection of science fiction stories explores the allegorical overtones about the precariousness of species. Biogenesis and Other Stories collects five stories by Tatsuaki Ishiguro. In Biogenesis, two professors research the rare winged mouse and how the genetic makeup of the creatures pointed to their eventual extinction. The discover that upon mating, both the male and female of the species died. The professors try to clone the winged mice without success, so they breed the remaining pair in captivity, noting the procedure, which includes a vibration of the creatures' wings, what appeared to be kissing, and the shedding of tears--composed of the same substance as their blood--until their eventual death.


Theories of Life's Origin

Author: Emeritus Professor of Origin of Life and Soil Science Noam Lahav,Noam Lahav

Publisher: Oxford University Press, USA

ISBN: 9780195117547

Category: Science

Page: 349

View: 1022

Biogenesis provides an up-to-date and detailed discussion of the interdisciplinary study of the origin of life, including in-depth investigations into its history, assumptions, experimental strategies, theories, models, and controversies. Written both critically and objectively, the book explores topics including the history of the search for life's origin from the Greek philosophers to contemporary scientists; selected attributes of life which are connected to theories of biogenesis; the main features of our solar system and earth, where life is assumed to have originated; and the rationale and strategies of scientific theories of the origin of life. Filled with fascinating insights, Biogenesis will appeal to a wide range of scientists and students in biology, chemistry, and geology.

Biogenesis of Natural Compounds

Author: Peter Bernfeld

Publisher: Elsevier

ISBN: 1483184099

Category: Science

Page: 1224

View: 341

Biogenesis of Natural Compounds, Second Edition is released to provide updated information on the biogenesis of natural compounds. Most of the chapters in this book are rewritten, and new author contributes a paper on the biogenesis of proteins. This edition also includes a new chapter that deals with the formation of carcinogenic polynuclear hydrocarbons. However, all other chapters are maintained; some of which have modified headings. This edition will help those studying the biogenesis of natural compounds and in need of more updated information compared to those presented in the previous edition.

Membrane Biogenesis

Mitochondria, Chloroplasts, and Bacteria

Author: Alexander Tzagoloff

Publisher: Springer Science & Business Media

ISBN: 1468421360

Category: Science

Page: 460

View: 6834

There are currently a growing number of laboratories actively studying the mechanism by which various biological membranes are assembled. This area of research is still relatively new to biochemists and molecular biologists, but in view of the rapid progress being made, a review of the field at this time is justified. The present volume focuses on the biogenesis of three related membranes. Mitochondria and chloroplasts are semiautonomous organelles whose biogenesis is carried out partly in the external cytoplasm and partly by the organelles themselves. Both membranes are principally concerned with the energy metabolism of the cell, and this commonality of function is reflected in a considerable degree of similarity in their ul trastructure and enzymatic composition. Although the bacterial cell membrane is a much more diversified structure, it also fulfills the basic energy requirements of the cell, and depending on the organism, this can take the form of photosynthesis or oxidative phosphorylation. The addi tional consideration that prokaryotic organisms may, in fact, be the evolu tionary ancestors of mitochondria and chloroplasts, makes it all the more compelling that those interested in biogenesis be aware of new develop ments in each of these three areas. In organizing this book, I felt that the contributors should summarize and bring up to date their own research and review the literature only in sofar as would be necessary to provide the proper perspective for their work.

Biogenesis of Antibiotic Substances

Author: Zdenko Vanek

Publisher: Elsevier

ISBN: 0323155839

Category: Science

Page: 324

View: 1366

Biogenesis of Antibiotic Substances covers the proceedings of a panel discussion on ""Basic Research and Practical Aspects of Antibiotic Production"" held during the Antibiotic Congress in Prague. This book is organized into 25 chapters that cover the regulating mechanisms of primary antibiotic metabolite biosynthesis. This text describes the relationship between secondary metabolite production and synthesis of cell matter or cell wall. The opening chapters describe the parasexual cycle and some of the ways in which the cycle may be used for strain improvement, as well as the applications of refined techniques of genetic recombination and the principles of biochemical genetics to the field of antibiotics. The next chapter deals with cultural and fermentative characteristics of A-type isolates obtained from progenitor and representative member strains of the Wisconsin Family of Strains of Penicillium chrysogenum. Considerable chapters are devoted to the metabolite biosynthesis, such as geodoxin and related compounds; secondary metabolism of penicillins, gibberellins, and griseofulvin in fungi; and tetracycline metabolites. The book goes on examining the stereochemical aspects of macrolide antibiotics. It also describes the biosynthetic pathways involving ring cleavage of carbocyclic compounds, as well as the biosynthesis of different peptide antibiotics and of actinomycins and its relationship to protein synthesis. The production of phenazines is also explained. Other chapters consider other metabolites, such as those that decarboxylate, the malonate, and the 3-nitropropionic acid. A discussion on the role of carbohydrates and phosphate in the biosynthesis of different types of antibiotics is included. Lastly, microbiological assay procedures for antibiotic research and influencing factors are presented.

Blood Sport

A-Rod and the Quest to End Baseball's Steroid Era

Author: Tim Elfrink,Gus Garcia-Roberts

Publisher: Penguin

ISBN: 0147516269

Category: Self-Help

Page: 480

View: 1174

"First published in the United States of America by Dutton, a member of Penguin Group (USA) LLC, 2014"--T.p. verso.

Baseball Cop

Author: Eddie Dominguez

Publisher: Hachette Books

ISBN: 0316483990

Category: Biography & Autobiography

Page: 304

View: 8133

Exposing trafficking, theft, fraud, and gambling in the major leagues, a founding member of the MLB's Department of Investigations reveals a news-breaking true story of power and corruption. In the wake of 2005's sometimes contentious, sometimes comical congressional hearings on performance-enhancing drugs in baseball and the subsequent Mitchell Report, Major League Baseball established the Department of Investigations (DOI). An internal and autonomous unit, it was created to not only eliminate the use of steroids, but also to rid baseball of any other illegal, unsavory, or unethical activities. The DOI would investigate the dark side of the national pastime--gambling, age and identity fraud, human trafficking, cover-ups, and more--with the singular purpose of cleaning up the game. Eduardo Dominguez Jr. was a founding member of that first DOI team, leaving a stellar career with the Boston Police Department to join four other "supercops"--a group that included a 9/11 hero, a mob-buster, and narcotics experts--keeping watch over Major League Baseball. A decorated detective as well as a member of an FBI task force, Dominguez was initially reluctant to leave his law-enforcement career to work full-time in baseball. He had already seen the game's underbelly when he worked as a resident security agent (RSA) for the Boston Red Sox in 1999 and become wary of the game's commitment to any kind of reform. Only at the persuasion a widely respected NYPD detective tapped to lead the DOI did Dominguez agree to join the unit, which was the first--and last--of its kind in major American sports. "We could clean up this game," his new boss promised. In Baseball Cop, Dominguez shares the shocking revelations he confronted every day for six years with the DOI and nine as an RSA. He shines a light on the inner workings of the commissioner's office and the complicity of baseball's bosses in dealing with the misdeeds compromising the integrity of the game. Dominguez details the investigations and the obstacles--from the Biogenesis scandal to the perilous trafficking of Cuban players now populating the game to the theft of prospects' signing bonuses by buscones, street agents, and even clubs' employees. He further reveals how the mandates of former senator George Mitchell's report were modified or ignored altogether. Bracing and eye-opening, Baseball Cop is a wake-up call for anyone concerned about America's national pastime.

Prostaglandins, Leukotrienes, and Other Eicosanoids

From Biogenesis to Clinical Application

Author: Friedrich Marks,Gerhard Fürstenberger

Publisher: John Wiley & Sons

ISBN: 3527613633

Category: Science

Page: 408

View: 616

Polyunsaturated fatty acids are essential for human cell metabolism. As precursors of a very large and extremely versatile family of signaling compounds they play a key role in intracellular communication. Eicosanoids constitute one of the most abundant and prominent subfamilies of these fatty acid derivatives which are formed primarily along oxidative pathways. Prostaglandins, leukotrienes, and related eicosanoids have a modulatory function in mammalian cells and are responsible for tissue responses such as inflammation or wound repair. Increasing activity in eicosanoid research sheds new light on today's most common diseases including atherosclerosis, cancer, Alzheimer's, allergies, and rheumatic diseases. The recent advances already have far-reaching implications in medicine. This detailed account, written by leading experts, covers the ground-breaking developments in recent eicosanoid research. The topics span eicosanoid biogenesis, new aspects of their pathophysiology, for example their influence on the cardiovascular system, as well as the clinical application of synthetic eicosanoids and their antagonists. Researchers and students working in biochemistry or in pharmaceutical, physiological, medicinal and neurochemistry will value this informative introduction to one of the most rapidly developing fields in cell biology.


Theories of Life's Origin

Author: Noam Lahav

Publisher: ICON Group International


Category: Science

Page: 349

View: 8541

Biogenesis provides an up-to-date and detailed discussion of the interdisciplinary study of the origin of life, including in-depth investigations into its history, assumptions, experimental strategies, theories, models, and controversies. Written both critically and objectively, the book explores topics including the history of the search for life's origin from the Greek philosophers to contemporary scientists; selected attributes of life which are connected to theories of biogenesis; the main features of our solar system and earth, where life is assumed to have originated; and the rationale and strategies of scientific theories of the origin of life. Filled with fascinating insights, Biogenesis will appeal to a wide range of scientists and students in biology, chemistry, and geology.

Biogenesis Of Plant Cell Wall Polysaccharides

Author: Frank Loewus

Publisher: Elsevier

ISBN: 0323152465

Category: Science

Page: 394

View: 5914

Biogenesis of Plant Cell Wall Polysaccharides contains the proceedings of a 1972 symposium on Biogenesis of Plant Cell Wall Polysaccharides held at the 164th National Meeting of the American Chemical Society, New York, New York. The symposium focuses on a broad range of interest from structural to functional aspects of cell wall polysaccharide biosynthesis in algae as well as in higher plants. Organized into 17 chapters, this book details the progress and understanding regarding the biosynthesis of cell wall components and the assembly of these components in the wall. It encompasses topics on cell wall polysaccharides, UDP-D-glucuronic acid pyrophosphorylase, and D-xylose. This reference also tackles the UDP-D-glucuronic acid, L-arabinose, D-apiose, and carbohydrate polymers. Furthermore, it explains other topics, such as on extensin, hydroxyproline-rich glycoprotein, cellulose, and polygalacturonic acid.


Author: Terence West

Publisher: Double Dragon Publishing

ISBN: 1554042216

Category: Fiction

Page: N.A

View: 4527

The Biogenesis of Cellular Organelles

Author: Chris Mullins

Publisher: Springer Science & Business Media

ISBN: 0387268677

Category: Medical

Page: 181

View: 8787

The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the endoplasmic reticulum, Golgi, lysosome, nucleus, mitochondria, and peroxisome.


Book 2 of the Earthborn

Author: Adair Hart

Publisher: Quantum Edge Publishing

ISBN: 8828328282

Category: Fiction

Page: N.A

View: 9698

There is always something scarier out there After a successful first mission and a month off, Blake Brown and crew head out on a new mission to the remote Zolidack system. A classified research facility has been sighted with the presence of illegal cargo that relates to what they found on their previous mission. The problem is the system is controlled by the Fredorian Defense Force, a group who dislikes Earthborn of any stripe. The facility is operated by the Dorostatic Initiatives Corporation, which is recovering from a genetic engineering scandal and hates any government intrusion, Earthborn or not. Getting to the facility is one challenge. Dealing with a new crew problem while doing it is another. To make matters worse, brutal, bug-like Rogundan mercenary slavers have been spotted in the system. Blake and crew will do all they can to investigate the facility while navigating both internal and external threats. If there’s one thing Earthborn can do well, it’s adapt, and Blake and crew will show everyone how it’s done.

Membrane Biogenesis and Protein Targetting

Author: W. Neupert,R. Lill

Publisher: Elsevier

ISBN: 9780080860824

Category: Science

Page: 340

View: 765

This book provides a comprehensive overview of recent developments in the fast moving field of protein transport across and into intracellular membranes. The soluble and membrane-bound components assisting in these processes are introduced, and their functions described. Besides a detailed analysis of protein translocation across the bacterial plasma membrane, the mechanisms of protein targeting within the eukaryotic cell are discussed with special focus on the transport of proteins to the endoplasmic reticulum, vacuoles, peroxisomes, mitochondria, and chloroplasts. Providing stimulating hypotheses and models, the book is well suited for advanced students, graduate students, and for newcomers to the field seeking a general, yet accurate introduction to present knowledge in membrane transport of proteins.

Mitochondrial Function and Biogenesis

Author: Carla Koehler,Matthias F. Bauer

Publisher: Springer Science & Business Media

ISBN: 9783540214892

Category: Medical

Page: 333

View: 9148

This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. (Cover)

Intracellular Pathogens in Membrane Interactions and Vacuole Biogenesis

Author: Jean-Pierre Gorvel

Publisher: Springer Science & Business Media

ISBN: 9780306478338

Category: Medical

Page: 301

View: 6754

This book provides information on the molecular interactions between host cell organelles and pathogens, which have developed strategies to survive within infected cells. Chapters are grouped into five sections: I. Endocytosis and phagocytosis. Collectively, the chapters of this section review basic knowledge regarding intracellular organelles are involved in membrane interactions with pathogen-containing vacuoles. II. Professional and non-professional phagocytes. Here the authors describe the major differences between the two host cell types, which can be infected by microorganisms. III. Maturation pathways of bacteria-containing vacuoles. Molecular interactions between vacuoles and intracellular organelles leading to the search of the Holy Grail, the replication niche, are described. IV. Host response. Host cells are able to react against intruders and eventually mount host responses. In these chapters the various types of host response mechanisms against intracellular intruders are reviewed. V. Co-evolution. In these final chapters, the question is addressed of whether knowledge of bacteria-host cell interactions will be acquired fast enough to find the necessary tools for controlling microorganism development.

Mitochondrial Biogenesis and Genetics

Author: Giuseppe Attardi

Publisher: Gulf Professional Publishing

ISBN: 9780121821654

Category: Science

Page: 621

View: 5002

The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 260 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * This volume covers methodology used in * Mitochondrial gene expression * Mitochondrial genetics and gene manipulation * Mitochondrial diseases and aging

Chloroplast Biogenesis

From Proplastid to Gerontoplast

Author: Udaya C. Biswal,M.K. Raval

Publisher: Springer Science & Business Media

ISBN: 9781402016028

Category: Science

Page: 353

View: 9136

Chloroplast is the organelle where the life-giving process photosynthesis takes place; it is the site where plants and algae produce food and oxygen that sustain our life. The story of how it originates from proplastids, and how it ultimately dies is beautifully portrayed by three authorities in the field: Basanti Biswal, Udaya Biswal and M. K. Raval. I consider it a great privilege and honor to have been asked to write this foreword. The book ' Chloroplast biogenesis: from proplastid to gerontoplast' goes much beyond photosynthesis. The character of the book is different from that of many currently available books because it provides an integrated approach to cover the entire life span of the organelle including its senescence and death. The books available are mostly confined to the topics relating to the 'build up' or development of chloroplast during greening. The story of organelle biogenesis without description of the events associated with its regulated dismantling during genetically programmed senescence is incomplete. A large volume of literature is available in this area of chloroplast senescence accumulated during the last 20 years. Although some of the findings in this field have been organized in the form of reviews, the data in the book are generalized and integrated with simple text and graphics. This book describes the structural features of prop las tid and its transformation to fully mature chloroplast, which is subsequently transformed into gerontoplast exhibiting senescence syndrome. The book consists of five major chapters.

Biogenesis of Natural Products

Author: Baldev Kumar,Harish Kumar Chopra

Publisher: Alpha Science Int'l Ltd.

ISBN: 9781842652824

Category: Science

Page: 296

View: 8059

Starting with photosynthesis, the authors have derived a very lucid, logical approach from CO2 and H2O to complicated structures of alkaloids, terpenes and many other natural products. This approach is based on the basic principles of Organic reaction mechanism which though taken from other research studies, have been shown to be followed in nature. In addition to the basic formulations of Acetate hypothesis, and Mevlonic pathways, newer non mevalonic paths have also been discussed and differences pointed out. As there is a limit to the inclusion of natural products in this text, only those cases are taken, in which basic principles are involved e.g. in alkaloids biosynthesis and basic amino acids which show their pathway in biosynthesis. The material has been arranged in a sequence as to how a teacher of biosynthesis should/would teach this subject.